Mark Yeoman

2024

3D printed skyscraper electrochemical biosensor for the detection of tumour necrosis factor alpha (TNFα) in faeces

Hussain, K., Hopkins, R., Yeoman, M. & Patel, B., 22 Mar 2024, In: Sensors and Actuators, B: Chemical. 410, 135694.

Research output: Contribution to journal › Article › peer-review

Open Access

Amperometry approach curve profiling to understand the regulatory mechanisms governing the concentration of intestinal extracellular serotonin

Yeoman, M., Fidalgo, S., Marcelli, G. & Patel, B., 7 May 2024, In: Scientific Reports. 14, 1, 10479 (2024).

Research output: Contribution to journal › Article › peer-review

Open Access

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Decreases in mucosally-evoked tachykinin signaling pathways can explain age-related reductions in murine colonic motility patterns

Yeoman, M. S., Fidalgo, S., Hobby, I., Hafeez, A., Ranson, R. N., Saffrey, M. J. & Patel, B. A., 18 Aug 2024, In: Neurogastroenterology and Motility. 36, 11, 11 p., e14891.

Research output: Contribution to journal › Article › peer-review

Open Access

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Subsets of Nanometer Vesicles in the Fly Release Differential Fractions of Vesicular Serotonin Content during Exocytosis

Gu, C., Wang, Y., Yeoman, M., Patel, B. A. & Ewing, A., 5 Aug 2024, In: Angewandte Chemie-International Edition. 63, 44, 6 p., e202409783.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Age-Related Changes in Central Nervous System 5-Hydroxytryptamine Signalling and Its Potential Effects on the Regulation of Lifespan

Sara Fidalgo & Yeoman, M., 5 Jan 2023, Biochemistry and Cell Biology of Ageing: Part III Biomedical Science. Harris, J. R. & Korolchuk, V. (eds.). 3 ed. Switzerland: Springer Nature, Vol. 102. p. 379-413 35 p. (Sub-cellular biochemistry).

Research output: Chapter in Book/Conference proceeding with ISSN or ISBN › Chapter › peer-review

Open Access

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Exploring Different Carbon Allotrope Thermoplastic Composites for Electrochemical Sensing

Hussain, K. K., Shergill, R. S., Hamzah, H. H., Yeoman, M. S. & Patel, B. A., 10 May 2023, In: ACS Applied Polymer Materials. 5, 6, p. 4136-4145 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2022

Glucocorticoid induced loss of oestrogen receptor alpha gene methylation and restoration of sensitivity to fulvestrant in triple negative breast cancer

Intabli, H., Gee, J., Oesterreich, S., Yeoman, M., Allen, M., Qattan, A. & Flint, M., 5 Nov 2022, In: Gene. 851, 147022.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Decreased 14‐3‐3 expression correlates with age‐related regional reductions in CNS dopamine and motor function in the pond snail, Lymnaea

Morgan, L. D., Aiyaz, M., Patel, B., Arundell, M., Jennert‐Burtson, K., Hernádi , L., Overall, A., Bowler, L., O'Hare, D. & Yeoman, M., 1 Nov 2020, In: European Journal of Neuroscience. p. 1-18

Research output: Contribution to journal › Article › peer-review

Open Access

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Effects of age and social isolation on murine hippocampal biochemistry and behavior

Panossian, A., Cave, M. W., Patel, B., Brooks, E. L., Flint, M. & Yeoman, M., 28 Aug 2020, In: Mechanisms of Ageing and Development. 191, 111337.

Research output: Contribution to journal › Article › peer-review

2019

Determination of tryptophan metabolism from biological tissues and fluids using high performance liquid chromatography with simultaneous dual electrochemical detection

Brooks, E., Mutengwa, V., Abdalla, A., Yeoman, M. & Patel, B., 16 Sept 2019, In: Analyst. 144, 20, p. 6011-6018 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Region specific differences in the effect of propofol on the murine colon result in dysmotility

Diss, L., Villeneuve, S., Pearce, K., Yeoman, M. & Patel, B., 29 Mar 2019, In: Autonomic Neuroscience-Basic & Clinical. 219, p. 19-24 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Three-Dimensional-Printed Electrochemical Sensor for Simultaneous Dual Monitoring of Serotonin Overflow and Circular Muscle Contraction

Bin Hamzah, H., Keattch, O., Yeoman, M., Covill, D. & Patel, B., 27 Aug 2019, In: Analytical Chemistry. 91, 18, p. 12014-12020 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2018

BBSRC Pathfinder - Technology Market Assessment and Patent Landscape Analysis for use of TNF-α Antagonists in the Management of Constipation in the Elderly

Yeoman, M. & Patel, B., 2018, 54 p.

Research output: Book/Report › Commissioned report

File

Changes in murine anorectum signaling across the life course

Fidalgo, S., Patel, B., Ranson, R., Saffrey, J. & Yeoman, M., 30 Jul 2018, In: Neurogastroenterology and Motility. 30, 10, p. 13426-13438 13 p., e13426.

Research output: Contribution to journal › Article › peer-review

Open Access

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Does the 5-HT1A rs6295 polymorphism influence the safetyand efficacy of citalopram therapy in the oldest old?

Scutt, G., Overall, A., Scott, R., Patel, B., Hachoumi, L., Yeoman, M. & Wright, J., 23 Apr 2018, In: Therapeutic Advances in Drug Safety. 9, 7, p. 355-366

Research output: Contribution to journal › Article › peer-review

Open Access

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Interstitial cell network volume is reduced in the terminal bowel of ageing mice

Gamage, P. P. K. M., Patel, B. A., Yeoman, M. S., Ranson, R. N. & Jill Saffrey, M., 25 Jul 2018, In: Journal of Cellular and Molecular Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2017

The TNF-α antagonist etanercept reverses age-related decreases in colonic SERT expression and faecal output in mice

Patel, B., Fidalgo, S., Wang, C., Parmar, L., Mandona, K., Panossian, A., Flint, M., Ranson, R. N., Saffrey, M. J. & Yeoman, M., 15 Feb 2017, In: Scientific Reports. 7, p. 1-12 12 p., 42754.

Research output: Contribution to journal › Article › peer-review

Open Access

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2016

Acute paraquat exposure impairs colonic motility by selectively attenuating nitrergic signaling in the mouse

Diss, L., Dyball, S., Ghela, T., Golding, J., Morris, R., Robinson, S., Tucker, R., Walter, T., Young, P., Allen, M., Fidalgo, S., Gard, P., Mabley, J., Patel, B., Chatterjee, P. & Yeoman, M., 30 Jan 2016, In: Autonomic Neuroscience-Basic & Clinical. 195, p. 8-15 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Does Age Matter? The Impact of Rodent Age on Study Outcomes

Jackson, S., Andrews, N., Ball, D., Bellatntuono, L., Gray, J., Hachoumi, L., Holmes, A., Latcham, J., Petrie, A., Potter, P., Rice, A., Ritchie, A., Stewart, M., Strepka, C., Yeoman, M. & Chapman, K., 15 Jun 2016, In: Laboratory Animals. 51, 2, p. 160-169 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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Electrochemical sensor for the detection of multiple reactive oxygen and nitrogen species from ageing central nervous system homogenates

Fagan-Murphy, A., Hachoumi, L., Yeoman, M. & Patel, B., 14 Oct 2016, In: Mechanisms of Ageing and Development. 160, p. 28-31 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2015

A switch in the mode of the sodium/calcium exchanger underlies an age-related increase in the slow afterhyperpolarization

Scutt, G., Allen, M., Kemenes, G. & Yeoman, M., 1 Oct 2015, In: Neurobiology of Aging. 36, 10, p. 2838-2849 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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2014

Impaired colonic motility and reduction in tachykinin signalling in the aged mouse

Patel, B., Patel, N., Fidalgo, S., Wang, C., Ranson, R. N., Saffrey, M. J. & Yeoman, M., 31 May 2014, In: Experimental Gerontology. 53, p. 24-30 7 p.

Research output: Contribution to journal › Article › peer-review

2013

Age-related changes in melatonin release in the murine distal colon

Diss, L. B., Robinson, S. D., Wu, Y., Fldalgo, S., Yeoman, M. & Patel, B., 30 Apr 2013, In: ACS Chemical Neuroscience. 4, 5, p. 879-887 9 p.

Research output: Contribution to journal › Article › peer-review

Biomarkers, interventions and healthy ageing

Kenessary, A., Zhumadilov, Z., Nurgozhin, T., Kipling, D., Yeoman, M., Cox, L., Ostler, E. & Faragher, R., 25 May 2013, In: New Biotechnology. 30, 4, p. 373-377 5 p.

Research output: Contribution to journal › Article › peer-review

Changes in the innervation of the mouse internal anal sphincter during aging

Wang, C., Houghton, M. J., Gamage, P. P. K. M., Collins, H. E., Patel, B., Yeoman, M., Ranson, R. N. & Saffrey, M. J., 1 May 2013, In: Neurogastroenterology and Motility. 25, 7

Research output: Contribution to journal › Article › peer-review

Myenteric neuron numbers are maintained in aging mouse distal colon

Gamage, P. P. K. M., Ranson, R. N., Patel, B., Yeoman, M. & Saffrey, M. J., 20 Mar 2013, In: Neurogastroenterology and Motility. 25, 7

Research output: Contribution to journal › Article › peer-review

2012

Age-related change in cholinergic and nitrergic signaling in the mouse rectum

Patel, B., Fidalgo, S., Ranson, R. N., Saffrey, M. J. & Yeoman, M., 30 Sept 2012, p. 120-120. 1 p.

Research output: Contribution to conference › Abstract

Age-related changes in colonic motility, faecal output and the properties of faecal pellets in the mouse

Patel, B., Patel, N., Fidalgo, S., Ranson, R. N., Saffery, J. & Yeoman, M., 30 Sept 2012, In: Neurogastroenterology and Motility. 24

Research output: Contribution to journal › Article › peer-review

Analysis of changes in the cells of the mouse internal anal sphincter during aging

Saffrey, M. J., Wang, C., Gamage, P. P. K. M., Davies, H., Colyer, F., Houghton, M. J., Patel, B., Yeoman, M. & Ranson, R. N., 30 Sept 2012, p. 125-125. 1 p.

Research output: Contribution to conference › Abstract

Chromatographic analysis of age-related changes in mucosal serotonin transmission in the murine distal ileum

Parmar, L., Fidalgo, S., Yeoman, M. & Patel, B., 31 Dec 2012, In: Chemistry Central Journal. 6, 1

Research output: Contribution to journal › Article › peer-review

Open Access

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Chromatographic assay to study the activity of multiple enzymes involved in the synthesis and metabolism of dopamine and serotonin

Patel, B., Yeoman, M., Morgan, L. D. & Baker, H., 31 Dec 2012, In: Analyst. 137, 6, p. 1409-1415 7 p.

Research output: Contribution to journal › Article › peer-review

Decrease in serotonin-induced tachykinin signaling can account for age: Related reductions in the amplitude and the frequency of Colonic Migrating Motor Complexes (CMMCS) in the murine distal colon

Patel, B., Yeoman, M., Fidalgo, S., Dhulia, P., Girdlestone, I., Ranson, R. N. & Saffrey, M. J., 30 Sept 2012, In: Neurogastroenterology and Motility. 24, p. 128-128 1 p.

Research output: Contribution to journal › Article › peer-review

Effect of age on mucosal serotonin signalling and circular muscle contractions in the murine rectum

Patel, B., Parmar, L., Fidalgo, S., Wang, C., Ranson, R. N., Saffrey, M. J. & Yeoman, M., 30 Sept 2012, p. 84-84. 1 p.

Research output: Contribution to conference › Abstract

Insights into CNS ageing from animal models of senescence

Yeoman, M., Scutt, G. & Faragher, R., 30 Jun 2012, In: Nature Reviews Neuroscience. 13, 6, p. 435-445 11 p.

Research output: Contribution to journal › Article › peer-review

2011

The effect of Alzheimer's disease - Associated β-amyloid peptide on voltage-dependant currents in a human-derived cell line

MacKenzie, L., Killock, R., Mayne, L. & Yeoman, M. S., 12 Apr 2011, In: Journal of Pharmacy and Pharmacology. 50, S9, 1 p.

Research output: Contribution to journal › Article › peer-review

2010

Microelectrode investigation of neuroneal ageing from a single identified neurone

Patel, B., Arundell, M., Parker, K. H., Yeoman, M. & O'Hare, D., 12 Jul 2010, In: Physical Chemistry Chemical Physics. 12, 34, p. 10065-10072 8 p.

Research output: Contribution to journal › Article › peer-review

2009

Transcriptome analysis of the central nervous system of the mollusc Lymnaea stagnalis

Feng, Z. P., Zhang, Z., Van Kesteren, R. E., Straub, V. A., Van Neirop, P., Jin, K., Nejatbakhsh, N., Goldberg, J. I., Spencer, G. E., Yeoman, M. S., Wildering, W., Coorssen, J. R., Croll, R. P., Buck, L. T., Syed, N. I. & Smit, A. B., 2009, In: BMC Genomics. 10, 451

Research output: Contribution to journal › Article › peer-review

Open Access

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2008