Mark Yeoman &ndash; Research Output

2019

3D Printed Electrochemical Sensor for Simultaneous Dual Monitoring of Serotonin Overflow and Circular Muscle Contraction

Bin Hamzah, H., Keattch, O., Yeoman, M., Covill, D. & Patel, B., 27 Aug 2019, In : Analytical Chemistry.

Research output: Contribution to journal › Article › Research › peer-review

Muscle Contraction

Serotonin

Soot

Equipment and Supplies

Fluoxetine

Region specific differences in the effect of propofol on the murine colon result in dysmotility

Diss, L., Villeneuve, S., Pearce, K., Yeoman, M. & Patel, B., 29 Mar 2019, In : Autonomic Neuroscience-Basic & Clinical. 219, p. 19-24 6 p.

Research output: Contribution to journal › Article › Research › peer-review

Propofol

Colon

Maintenance

Intravenous Anesthetics

Nitric Oxide Synthase

2018

BBSRC Pathfinder - Technology Market Assessment and Patent Landscape Analysis for use of TNF-α Antagonists in the Management of Constipation in the Elderly

Yeoman, M. & Patel, B., 2018, 54 p.

Research output: Book/Report › Commissioned report › Research

File

Biomedical Technology Assessment

Constipation

Drug Prescriptions

Immunologic Factors

Ulcerative Colitis

Changes in murine anorectum signaling across the life course

Fidalgo, S., Patel, B., Ranson, R., Saffrey, J. & Yeoman, M., 30 Jul 2018, In : Neurogastroenterology and Motility. 30, 10, p. 13426-13438 13 p., e13426.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Fecal Impaction

Acetylcholine

Constipation

Cholinergic Agents

Nitric Oxide

Does the 5-HT1A rs6295 polymorphism influence the safetyand efficacy of citalopram therapy in the oldest old?

Scutt, G., Overall, A., Scott, R., Patel, B., Hachoumi, L., Yeoman, M. & Wright, J., 23 Apr 2018, In : Therapeutic Advances in Drug Safety. 9, 7, p. 355-366

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Citalopram

Genotype

Major Depressive Disorder

Bayes Theorem

Antidepressive Agents

Interstitial cell network volume is reduced in the terminal bowel of ageing mice

Gamage, P. P. K. M., Patel, B. A., Yeoman, M. S., Ranson, R. N. & Jill Saffrey, M., 25 Jul 2018, In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Interstitial Cells of Cajal

Cell Size

Gastrointestinal Tract

Anal Canal

Rectum

2017

The TNF-α antagonist etanercept reverses age-related decreases in colonic SERT expression and faecal output in mice

Patel, B., Fidalgo, S., Wang, C., Parmar, L., Mandona, K., Panossian, A., Flint, M., Ranson, R. N., Saffrey, M. J. & Yeoman, M., 15 Feb 2017, In : Scientific Reports. 7

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Hydroxyindoleacetic Acid

Constipation

Water

Colon

Etanercept

2016

Acute paraquat exposure impairs colonic motility by selectively attenuating nitrergic signaling in the mouse

Diss, L., Dyball, S., Ghela, T., Golding, J., Morris, R., Robinson, S., Tucker, R., Walter, T., Young, P., Allen, M., Fidalgo, S., Gard, P., Mabley, J., Patel, B., Chatterjee, P. & Yeoman, M., 30 Jan 2016, In : Autonomic Neuroscience-Basic & Clinical. 195, p. 8-15 8 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Paraquat

Migrating Myoelectric Complexes

Gastrointestinal Tract

Colon

Myenteric Plexus

Does Age Matter? The Impact of Rodent Age on Study Outcomes

Jackson, S., Andrews, N., Ball, D., Bellatntuono, L., Gray, J., Hachoumi, L., Holmes, A., Latcham, J., Petrie, A., Potter, P., Rice, A., Ritchie, A., Stewart, M., Strepka, C., Yeoman, M. & Chapman, K., 15 Jun 2016, In : Laboratory Animals. 51, 2, p. 160-169 10 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Rodentia

Outcome Assessment (Health Care)

Research Design

Cell Aging

Research

Electrochemical sensor for the detection of multiple reactive oxygen and nitrogen species from ageing central nervous system homogenates

Fagan-Murphy, A., Hachoumi, L., Yeoman, M. & Patel, B., 14 Oct 2016, In : Mechanisms of Ageing and Development. 160, p. 28-31 4 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

2015

A switch in the mode of the sodium/calcium exchanger underlies an age-related increase in the slow afterhyperpolarization

Scutt, G., Allen, M., Kemenes, G. & Yeoman, M., 1 Oct 2015, In : Neurobiology of Aging. 36, 10, p. 2838-2849 12 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Sodium-Calcium Exchanger

Giant Cells

Cell Aging

Lymnaea

Snails

2014

Impaired colonic motility and reduction in tachykinin signalling in the aged mouse

Patel, B., Patel, N., Fidalgo, S., Wang, C., Ranson, R. N., Saffrey, M. J. & Yeoman, M., 31 May 2014, In : Experimental Gerontology. 53, p. 24-30 7 p.

Research output: Contribution to journal › Article › Research › peer-review

2013

Age-related changes in melatonin release in the murine distal colon

Diss, L. B., Robinson, S. D., Wu, Y., Fldalgo, S., Yeoman, M. & Patel, B., 30 Apr 2013, In : ACS Chemical Neuroscience. 4, 5, p. 879-887 9 p.

Research output: Contribution to journal › Article › Research › peer-review

Melatonin

Colon

Constipation

Serotonin

Fecal Impaction

Changes in the innervation of the mouse internal anal sphincter during aging

Wang, C., Houghton, M. J., Gamage, P. P. K. M., Collins, H. E., Patel, B., Yeoman, M., Ranson, R. N. & Saffrey, M. J., 1 May 2013, In : Neurogastroenterology and Motility. 25, 7

Research output: Contribution to journal › Article › Research › peer-review

Anal Canal

Nerve Fibers

Mucous Membrane

Nitric Oxide Synthase Type I

Muscles

Myenteric neuron numbers are maintained in aging mouse distal colon

Gamage, P. P. K. M., Ranson, R. N., Patel, B., Yeoman, M. & Saffrey, M. J., 20 Mar 2013, In : Neurogastroenterology and Motility. 25, 7

Research output: Contribution to journal › Article › Research › peer-review

Colon

Neurons

Nitric Oxide Synthase Type I

Nerve Fibers

Nitrergic Neurons

2012

Age-related change in cholinergic and nitrergic signaling in the mouse rectum

Patel, B., Fidalgo, S., Ranson, R. N., Saffrey, M. J. & Yeoman, M., 30 Sep 2012, p. 120-120. 1 p.

Research output: Contribution to conference › Abstract › Research

Age-related changes in colonic motility, faecal output and the properties of faecal pellets in the mouse

Patel, B., Patel, N., Fidalgo, S., Ranson, R. N., Saffery, J. & Yeoman, M., 30 Sep 2012, In : Neurogastroenterology and Motility. 24

Research output: Contribution to journal › Article › Research › peer-review

Analysis of changes in the cells of the mouse internal anal sphincter during aging

Saffrey, M. J., Wang, C., Gamage, P. P. K. M., Davies, H., Colyer, F., Houghton, M. J., Patel, B., Yeoman, M. & Ranson, R. N., 30 Sep 2012, p. 125-125. 1 p.

Research output: Contribution to conference › Abstract › Research

Chromatographic analysis of age-related changes in mucosal serotonin transmission in the murine distal ileum

Parmar, L., Fidalgo, S., Yeoman, M. & Patel, B., 31 Dec 2012, In : Chemistry Central Journal. 6, 1

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

Ileum

Chromatography

Serotonin

Hydroxyindoleacetic Acid

5-Hydroxytryptophan

Chromatographic assay to study the activity of multiple enzymes involved in the synthesis and metabolism of dopamine and serotonin

Patel, B., Yeoman, M., Morgan, L. D. & Baker, H., 31 Dec 2012, In : Analyst. 137, 6, p. 1409-1415 7 p.

Research output: Contribution to journal › Article › Research › peer-review

Decrease in serotonin-induced tachykinin signaling can account for age: Related reductions in the amplitude and the frequency of Colonic Migrating Motor Complexes (CMMCS) in the murine distal colon

Patel, B., Yeoman, M., Fidalgo, S., Dhulia, P., Girdlestone, I., Ranson, R. N. & Saffrey, M. J., 30 Sep 2012, In : Neurogastroenterology and Motility. 24, p. 128-128 1 p.

Research output: Contribution to journal › Article › Research › peer-review

Effect of age on mucosal serotonin signalling and circular muscle contractions in the murine rectum

Patel, B., Parmar, L., Fidalgo, S., Wang, C., Ranson, R. N., Saffrey, M. J. & Yeoman, M., 30 Sep 2012, p. 84-84. 1 p.

Research output: Contribution to conference › Abstract › Research

Insights into CNS ageing from animal models of senescence

Yeoman, M., Scutt, G. & Faragher, R., 30 Jun 2012, In : Nature Reviews Neuroscience. 13, 6, p. 435-445 11 p.

Research output: Contribution to journal › Article › Research › peer-review

2011

The effect of Alzheimer's disease - Associated β-amyloid peptide on voltage-dependant currents in a human-derived cell line

MacKenzie, L., Killock, R., Mayne, L. & Yeoman, M. S., 12 Apr 2011, In : Journal of Pharmacy and Pharmacology. 50, S9, 1 p.

Research output: Contribution to journal › Article › Research › peer-review

2010

Microelectrode investigation of neuroneal ageing from a single identified neurone

Patel, B., Arundell, M., Parker, K. H., Yeoman, M. & O'Hare, D., 12 Jul 2010, In : Physical Chemistry Chemical Physics. 12, 34, p. 10065-10072 8 p.

Research output: Contribution to journal › Article › Research › peer-review

Microelectrodes

Serotonin

Nitric Oxide

Lymnaea

Neurons

2009

Transcriptome analysis of the central nervous system of the mollusc Lymnaea stagnalis

Feng, Z. P., Zhang, Z., Van Kesteren, R. E., Straub, V. A., Van Neirop, P., Jin, K., Nejatbakhsh, N., Goldberg, J. I., Spencer, G. E., Yeoman, M. S., Wildering, W., Coorssen, J. R., Croll, R. P., Buck, L. T., Syed, N. I. & Smit, A. B., 2009, In : BMC Genomics. 10, 451

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

2008

Synapse-specific changes in serotonin signalling contribute to age-related changes in the feeding behaviour of the pond snail, Lymnaea

Yeoman, M., Patel, B., Arundell, M., Parker, K. & O'Hare, D., 28 Jun 2008, In : Journal of Neurochemistry. 106, 4, p. 1699-1709 11 p.

Research output: Contribution to journal › Article › Research

File

2007

Renin- angiotensin- system gene polymorphisms and depression

Saab, Y., Gard, P., Yeoman, M., El-Moalem, H., Mfarrej, B. & Ingram, M., 30 Jun 2007, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 31, 5, p. 1113-1118 6 p.

Research output: Contribution to journal › Article › Research › peer-review

Renin-Angiotensin System

Depression

Angiotensin Type 1 Receptor

Angiotensin Receptors

Genes

2006

Changes in the properties of the modulatory cerebral giant cells contribute to aging in the feeding system of Lymnaea

Patel, B., Arundell, M., Allen, M., Gard, P., O'Hare, D., Parker, K. & Yeoman, M., 1 Dec 2006, In : Neurobiology of Aging. 27, 12, p. 1892-1901 10 p.

Research output: Contribution to journal › Article › Research › peer-review

Lymnaea

Giant Cells

Feeding Behavior

Aptitude

Motor Neurons

Detection of nitric oxide release from single neurons in the pond snail, Lymnaea stagnalis

Patel, B., Arundell, M., Parker, K. H., Yeoman, M. & O'Hare, D., Aug 2006, In : Analytical Chemistry. 78, 22, p. 7643-7648 6 p.

Research output: Contribution to journal › Article › Research › peer-review

Effects of age on feeding behavior and chemosensory processing in the pond snail, Lymnaea stagnalis

Arundell, M., Patel, B., Straub, V., Allen, M., Janse, C., O'Hare, D., Parker, K., Gard, P. & Yeoman, M., Dec 2006, In : Neurbiology of Aging. 27, 12, p. 1880-1891 12 p.

Research output: Contribution to journal › Article › Research › peer-review

Lymnaea

Snails

Feeding Behavior

Sucrose

Lip

Novel subsecond voltametric separation betwen dopamine and serotonin in the presence of ascorbate

Anastassiou, C. A., Patel, B. A., Arundell, M., Yeoman, M., Parker, K. H. & O'Hare, D., Aug 2006, In : Analtical Chemistry. 78, 19, p. 6990-6998 9 p.

Research output: Contribution to journal › Article › Research › peer-review

Dopamine

Serotonin

Neurotransmitter Agents

Electric potential

Molecules

Subsecond voltametric separation between dopamine and serotonin in the presence of ascorbate

Anastassiou, C. A., Patel, B., Arundell, M., Yeoman, M., Parker, K. H. & O'Hare, D., Aug 2006, In : Analytical Chemistry. 78, 19, p. 6990-6998 9 p.

Research output: Contribution to journal › Article › Research › peer-review

Dopamine

Serotonin

Neurotransmitter Agents

Electric potential

Molecules

2005

Decreases in the serotonin content of a pair of identified neurones can explain the effect of p-chlorophenylanaline on the feeding behaviour of the pond snail, lymnaea stagnalis

Patel, B., Arundell, M., Parker, K., Yeoman, M. & O'Hare, D., 2005, In : Current Separations. 21, 2, p. 53-58 6 p.

Research output: Contribution to journal › Article › Research › peer-review

Simple and rapid determination of serotonin and catecholamines in biological tissue using high-performance liquid chromatography with electrochemical detection

Patel, B., Arundell, M., Parker, K. H., Yeoman, M. & O'Hare, D., Apr 2005, In : Journal of Chromatography B. 818, 2, p. 269-276 8 p.

Research output: Contribution to journal › Article › Research › peer-review

High performance liquid chromatography

Catecholamines

Serotonin

Tissue

Dopamine

2004

Electrodes

Glassy carbon

Electrochemistry

Fast Fourier transforms

Oxides

2001

Ageing and the nervous system: insights from studies on invertebrates

Yeoman, M. & Faragher, R., Jun 2001, In : Biogerontology. 2, 2, p. 85-97 13 p.

Research output: Contribution to journal › Article › Research › peer-review

Invertebrates

Nervous System

Neurons

Brain

1999

LVA and HVA Ca²⁺ currents in ventricular muscle cells of the Lymnaea heart

Yeoman, M. S., Brezden, B. L. & Benjamin, P. R., 14 Dec 1999, In : Journal of Neurophysiology. 82, 5, p. 2428-2440 13 p.

Research output: Contribution to journal › Article › Research › peer-review

Lymnaea

Cardiac Myocytes

Nifedipine

Ions

Excitation Contraction Coupling

Two types of voltage-gated K⁺ currents in dissociated heart ventricular muscle cells of the snail Lymnaea stagnalis

Yeoman, M. S. & Benjamin, P. R., 14 Dec 1999, In : Journal of Neurophysiology. 82, 5, p. 2415-2427 13 p.

Research output: Contribution to journal › Article › Research › peer-review

Lymnaea

Snails

Cardiac Myocytes

Action Potentials

Tetraethylammonium

1995

Identification, Distribution and Physiological Activity of Three Novel Neuropeptides of Lymnaea: FLRlamide and pQFYRlamide Encoded by the FMRFamide Gene, and a Related Peptide

Santama, N., Wheeler, C. H., Skingsley, D. R., Yeoman, M. S., Bright, K., Kaye, I., Burke, J. F. & Benjamin, P. R., 1 Jan 1995, In : European Journal of Neuroscience. 7, 2, p. 234-246 13 p.

Research output: Contribution to journal › Article › Research › peer-review

FMRFamide

Lymnaea

Neuropeptides

Peptides

Genes