Projects per year
Personal profile
Research interests
My Research interests focus on the use of genetic variation to provide insights into forensic science, genetic disease, molecular ecology and ageing. Past and current projects include the role of inbreeding and population substructure on forensic match calculations, the roles of selection and drift on rare genetic disorders, how ageing influences genetic drift and, most recently, SNP variation predicting response to chemotherapy amongst triple negative breast cancer patients.
Supervisory Interests
My supervisory interests include both in silico and in vitro explorations of how genetic information can inform our understanding of evolutionary biology and genetic health.
PhD Students
2017 - The molecular ecology of the British Hazel Dormouse.
2016 - Factors affecting vegetation change in chalk grassland fragments on the
South Downs.
2015 - The molecular ecology of the Sussex Water Vole populations.
2014 - The molecular ecology of the South African Jackal.
2013 - sodium symporter gene polymorphisms in the development of
differentiated thyroid cancer
2009 - Genetic variation underlying anxiety-like behaviour in laboratory mouse
strains.
MRes/MSci
2019 - Using human buccal cell telomere length as a predictor of age in a forensic
setting.
2015 - How does unidirectional gene flow affect genetic variation in the
Flagellate Feather Moss (Hylocomium armoricum) along rivers?
2008 - Molecular ecology of the flat periwinkle (Littorina obtusata).
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Network
Projects
- 1 Finished
-
Antidepressants in Older People
Yeoman, M., Scutt, G., Overall, A., Patel, B., Scott, R., Wright, J. & Hachoumi, L.
1/09/10 → 31/03/16
Project: Grant
Research Output
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Decreased 14‐3‐3 expression correlates with age‐related regional reductions in CNS dopamine and motor function in the pond snail, Lymnaea
Morgan, L. D., Aiyaz, M., Patel, B., Arundell, M., Jennert‐Burtson, K., Hernádi, L., Overall, A., Bowler, L., O'Hare, D. & Yeoman, M., 1 Nov 2020, In : European Journal of Neuroscience. p. 1-18Research output: Contribution to journal › Article
Open AccessFile -
Genetic structure of regional water vole populations and footprints of reintroductions: a case study from Southeast England
Baker, R., Scott, D., King, P. & Overall, A., 18 Mar 2020, In : Conservation Genetics. 21, 3, p. 531-546 16 p.Research output: Contribution to journal › Article
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Influence of Dominance and Drift on Lethal Mutations in Human Populations
Waxman, D. & Overall, A., 2 Apr 2020, In : Frontiers in Genetics. 11, 267.Research output: Contribution to journal › Article
Open AccessFile -
Lethal mutations with fluctuating heterozygous effect: the lethal force of effective dominance
Overall, A. & Waxman, D., 22 Jul 2020, In : Journal of Human Genetics. 65, 12, p. 1105-1113 9 p.Research output: Contribution to journal › Article
Open AccessFile -
Population type influences the rate of ageing
Overall, A. & Faragher, R., 8 Feb 2019, In : Heredity. 123, 2, p. 273-282 10 p.Research output: Contribution to journal › Article
Open AccessFile
Activities
- 1 Research degree
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Demographic and genetic patterns of water voles in human modified landscapes: implications for conservation
Dawn Scott (Supervisor), Andrew Overall (Supervisor) & Maureen Berg (Supervisor)
14 Jan 2016Activity: External examination and supervision › Research degree