If you made any changes in Pure these will be visible here soon.

Research Output 1999 2019

2019

Population type influences the rate of ageing

Overall, A. & Faragher, R., 8 Feb 2019, In : Heredity.

Research output: Contribution to journalArticleResearchpeer-review

Population
Survival Rate
Genetic Drift
Population Density
Gene Frequency

The association of a single nucleotide polymorphism in the nuclear factor erythroid derived-2 like 2 (Nrf-2) gene with adverse drug reactions, multimorbidity and frailty in older people

Scutt, G., Overall, A., Bakrania, P., Krasteva, E., Parekh, N., Ali, K., Davies, G. & Rajkumar, C., 18 May 2019, In : Journals of Gerontology, Series A.

Research output: Contribution to journalArticleResearchpeer-review

Drug-Related Side Effects and Adverse Reactions
Single Nucleotide Polymorphism
Comorbidity
Genes
Blood Cells
2018

Age-related changes to the expression of nuclear factor erythroid 2-like 2 (Nrf2), a regulatory antioxidant and xenobiotic defence gene

Scutt, G., Overall, A., Bakrania, P., Krasteva, E., Parekh, N., Ali, K., Davies, G. & Rajkumar, C., 2018, 14th International Congress of the European Geriatric Medicine Society: Advancing Geriatric Medicine in a Modern World. (European Geriatric Medicine).

Research output: Chapter in Book/Conference proceeding with ISSN or ISBNConference contribution with ISSN or ISBNResearchpeer-review

Xenobiotics
Antioxidants
Comorbidity
Drug-Related Side Effects and Adverse Reactions
Genes

Association of a regulatory anti-oxidant and drug-metabolising gene with multi-morbidity and adverse drug reactions in older adults

Scutt, G., Overall, A., Bakrania, P., Krasteva, E., Parekh, N., Ali, K., Davies, G. & Rajkumar, C., 2018.

Research output: Contribution to conferenceOtherResearchpeer-review

Drug-Related Side Effects and Adverse Reactions
Oxidants
Comorbidity
Morbidity
Pharmaceutical Preparations

Development of a High-Throughput ex-Vivo Burn Wound Model Using Porcine Skin, and Its Application to Evaluate New Approaches to Control Wound Infection

Ribeiro Alves, D., Booth, S., Scavone, P., Schellenberger, P., Salvage, J., Dedi, C., Thet, N-T., Jenkins, T. A., Waters, R., Ng, K. W., Overall, A., Metcalfe, A., Nzakizwanayo, J. & Jones, B., 15 Jun 2018, In : Frontiers in Cellular and Infection Microbiology. 196.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Wound Infection
Biofilms
Swine
Skin
Wounds and Injuries

Does the 5-HT1A rs6295 polymorphism influence the safetyand efficacy of citalopram therapy in the oldest old?

Scutt, G., Overall, A., Scott, R., Patel, B., Hachoumi, L., Yeoman, M. & Wright, J., 23 Apr 2018, In : Therapeutic Advances in Drug Safety. 9, 7, p. 355-366

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Citalopram
Genotype
Major Depressive Disorder
Bayes Theorem
Antidepressive Agents
2017

MRI-informed Biomimetic Design of Artificial Intervertebral Disc Scaffolds using 3D Bioplotting

Hodder, E., Covill, D., Bush, P., Cercignani, M., Dowell, N. G., Overall, A., Gelinsky, M., Lode, A. & Duin, S., 1 Dec 2017, p. 0-0. 1 p.

Research output: Contribution to conferenceAbstractResearch

Open Access
File
Biomimetics
Scaffolds (biology)
Magnetic resonance imaging
2016
Open Access
File
population size
microsatellite repeats
loci
homozygosity
alleles

First report of Laternula elliptica in the Antarctic intertidal zone

Waller, C. L., Overall, A., Fitzcharles, E. M. & Griffiths, H., 6 May 2016, In : Polar Biology. 40, 1, p. 227-230 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
intertidal environment
invertebrate
genetic analysis
sediment
warming

Food availability and population structure: How do clumped and abundant sources of carrion affect the genetic diversity of the black-backed jackal?

James, R. S., Scott, D., Yarnell, R. & Overall, A., 28 Oct 2016, In : Journal of Zoology.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
jackals
dead animals
food availability
population structure
genetic variation
2015
Open Access
File
jackals
Canis
microsatellite repeats
loci
endpoints

Heterozygote deficits in cyst plant-parasitic nematodes: possible causes and consequences

Montarry, J., Pierre-Loup, J., Gracianne, C., Overall, A., Bardou-Valette, S., Olivier, E., Fournet, S., Grenier, E. & Petit, E. J., 3 Apr 2015, In : Molecular Ecology. 24, 8, p. 1654-1677 24 p.

Research output: Contribution to journalArticleResearchpeer-review

plant parasitic nematodes
null alleles
heterozygosity
virulence
Nematoda

The Origins of the Co. Kildare Dormouse

Glass, D., Scott, D., Donoher, D. & Overall, A., 27 Apr 2015, In : Biology and Environment. 115B, 1, p. 1-6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Gliridae
haplotypes
Ireland
England
Wales

The potential role of the sodium iodide symporter gene polymorphism in the development of differentiated thyroid cancer

Al-Rasheed, M. M., Alzahrani, A. S., Macadam, A., Overall, A., Gard, P. & Dzimiri, N., 6 Jul 2015, In : Gene. 572, 2, p. 163-168 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Thyroid Neoplasms
Haplotypes
Single Nucleotide Polymorphism
Genes
Active Biological Transport
2013

The characteristic trajectory of a fixing allele: a consequence of fictitious selection that arises from conditioning

Zhao, L., Lascoux, M., Overall, A. & Waxman, D., 1 Nov 2013, In : Genetics. 195, 3, p. 993-1006 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Conditioning
Trajectory
Fixation
Finite Population
Progression
2012

The Eurasian water shrew: an unsuitable candidate species for a vertebrate bio-indicator of aquatic pollution

Scott, D., Southgate, F., Overall, A., Waite, S. & Tolhurst, B., 31 Jan 2012, In : Journal of Zoology. 286, 1, p. 30-37 8 p.

Research output: Contribution to journalArticleResearchpeer-review

bioindicator
vertebrate
water quality
pollution
water

The human-mirobiome co-evolutionary continuum

Ogilvie, L., Overall, A. & Jones, B., 2012, Microbial ecological theory: current perspectives. Ogilvie, L. & Hirsch, P. (eds.).

Research output: Chapter in Book/Conference proceeding with ISSN or ISBNChapterResearchpeer-review

2011

Strain differences and the role of AT1 receptor expression in anxiety

Golding, B. J., Overall, A. & Gard, P., 1 Jan 2011, In : International Journal of Molecular Epidemiology and Genetics, IJMEG. 2, 1, p. 51-55 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Angiotensin Receptors
Anxiety
Single Nucleotide Polymorphism
Proteins
Losartan

The association of hypertension with renin-angiotensin system gene polymorphisms in the Lebanese population

Saab, Y. B., Gard, P. & Overall, A., Dec 2011, In : Journal of the Renin-Angiotensin-Aldosterone System. 12, 7, p. 588-594 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The effect of population stratification on the frequency of compound heterozygosity

Overall, A., 10 Mar 2011, In : Genetica. 139, 3, p. 403-409 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The effect of substructure on the frequency of compound heterozygosity

Overall, A., 1 Jan 2011, In : Genetica.

Research output: Contribution to journalArticleResearchpeer-review

2010

Strain differences in the effects of Angiotensin IV on mouse cognition

Golding, B. J. D., Overall, A., Brown, G. & Gard, P., 1 Sep 2010, In : European Journal of Pharmacology. 641, 2-3, p. 154-159 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
2008

Recessive disorders: Consanguinity and substructure in British Pakistani communities

Overall, A., 2008, Population Genetics Research Progress. Koven, V. T. (ed.). USA, p. 85-122 38 p.

Research output: Chapter in Book/Conference proceeding with ISSN or ISBNChapterResearchpeer-review

The role of IRAP in the effect of angiotensin IV on cognition in the mouse

Golding, B., Overall, A. & Gard, P., Aug 2008, p. 103-103. 1 p.

Research output: Contribution to conferenceAbstractResearchpeer-review

2007

The geographic distribution of the ACE II genotype: a novel finding

Saab, Y. B., Gard, P. & Overall, A., Aug 2007, In : Genetics Research. 89, 4, p. 259-267 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Peptidyl-Dipeptidase A
Genotype
Gene Frequency
Population
Geographic Locations
2005

Heterozygosity, inbreeding and neonatal traits in Soay sheep on St Kilda

Overall, A., Byrne, K. A., Pilkington, J. G. & Pemberton, J. M., Oct 2005, In : Molecular Ecology. 14, 11, p. 3383-3393 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Soay
inbreeding
heterozygosity
pedigree
sheep

Maternal genetic effects set the potential for evolution in a free-living vertebrate population

Wilson, A. J., Coltman, D. W., Pemberton, J. M., Overall, A., Byrne, K. A. & Kruuk, L. E. B., Mar 2005, In : Journal of Evolutionary Biology. 18, 2, p. 405-414 10 p.

Research output: Contribution to journalArticleResearchpeer-review

vertebrates
maternal effect
litter size
birth weight
heritability

Selection on mothers and offspring: whose phenotype is it and does it matter?

Wilson, A. J., Pilkington, J. G., Pemberton, J. M., Coltman, D. W., Overall, A., Byrne, K. A. & Kruuk, L. E. B., Feb 2005, In : Evolution. 59, 2, p. 451-463 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

Api-calc 1.0: a computer program for calculating the average probability of identity allowing for substructure, inbreeding and the presence of close relatives

Ayres, K. L. & Overall, A., Jun 2004, In : Molecular Ecology Notes. 4, 2, p. 315-318 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Apus
inbreeding
population structure
DNA fingerprinting
ecology
2003

An analysis of consanguinity and social structure within the UK asian population using microsatellite data

Overall, A., Ahmad, M., Thomas, M. G. & Nichols, R. A., Nov 2003, In : Annals of Human Genetics. 67, 6, p. 525-537 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Consanguinity
Microsatellite Repeats
Population
Marriage
Gene Frequency

Population genetic structure of the lettuce root aphid, Pemphigus bursarius (L.), in relation to geographic distance, gene flow and host plant usage

Miller, N. J., Birley, A. J., Overall, A. & Tatchell, G. M., Sep 2003, In : Heredity. 91, 3, p. 217-223 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Pemphigus bursarius
population genetics
gene flow
intermediate hosts
host plants
2002

The effect of reproductive compensation on recessive disorders within consanguineous human populations

Overall, A., Ahmad, M. & Nichols, R. A., Jun 2002, In : Heredity. 88, 6, p. 474-479 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Consanguinity
Population
Alleles
Inborn Genetic Diseases
Inbreeding
2001

A method for distinguishing consanguinity and population substructure using multilocus genotype data

Overall, A. & Nichols, R. A., Nov 2001, In : Molecular Biology and Evolution. 18, 11, p. 2048-2056 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2000

Patterns of paternal relatedness in British grey seal colonies

Wilmer, J. W., Overall, A., Pomeroy, P. P., Twiss, S. D. & Amos, W., 31 Mar 2000, In : Molecular Ecology. 9, 3, p. 283-292 10 p.

Research output: Contribution to journalArticleResearchpeer-review

seals
pups
breeding
Halichoerus grypus
social dominance
1999

Allowing for within-subpopulation inbreeding in forensic match probabilities

Ayres, K. L. & Overall, A., 9 Sep 1999, In : Forensic Science International. 103, 3, p. 207-216 10 p.

Research output: Contribution to journalArticleResearchpeer-review

deoxyribonucleic acid
coefficients