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Personal profile

Research interests

I am Professor of Biological Gerontology at the University of Brighton and past Chair of the British Society for Research on Ageing, the International Association of Biomedical Gerontology and the American Aging Association.  

I read Biochemistry at Imperial College, London and undertook doctoral studies at the University of Sussex. My primary research interest is the relationship between cellular senescence and organismal ageing.   

In 2002 my work on the accelerated ageing disease Werner’s syndrome led to the award of the Royal Pharmaceutical Society Conference Science Medal for outstanding scientific achievement.  In 2005 I became the first ever scientist to receive a Help the Aged award for my championship of older people and the use of research for their benefit.  

In 2010, I became the first ever British recipient of the Paul F Glenn Award for research into the biological mechanisms of the ageing process. I am a visiting Professor at the Moscow Institute of Physics and Technology and a Trustee of the Biogerontology Research Foundation.

I have served as a member of the Research Advisory Council of the Charity Research into Ageing and on strategy and funding panels for the BBSRC, the US National Institutes on Ageing and the European Union.  From 2005-2008 I was Co-director of the BBSRC-EPSRC SPARC programme, a research network designed to build national capacity to conduct inter-disciplinary ageing research. 

In 2015 I became the first British citizen to be elected to the Board of Directors of the American Federation for Aging Research, the leading US non-profit organization supporting and advancing healthy aging through biomedical research. In 2016 I was presented with the highest award for services to gerontology in the United Kingdom, the Lord Cohen of Birkenhead Medal and became a Fellow of the American Aging Association.

Education/Academic qualification

PhD, University of Sussex

Bachelor, Imperial College London

1 Oct 198630 Jun 1989

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Research Output 1997 2019

Population type influences the rate of ageing

Overall, A. & Faragher, R., 8 Feb 2019, In : Heredity.

Research output: Contribution to journalArticleResearchpeer-review

Population
Survival Rate
Genetic Drift
Population Density
Gene Frequency

FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence

Latorre, E., Ostler, E. L., Faragher, R. G. A. & Harries, L. W., 8 Aug 2018, In : The FASEB Journal.

Research output: Contribution to journalArticleResearchpeer-review

Cell Aging
MAP Kinase Signaling System
Genes
Fibroblasts
Gene Knockdown Techniques

Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing

Burton, D. G. A. & Faragher, R. G. A., 27 Jul 2018, In : Biogerontology. 19, 6, p. 447–459

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Cell Aging
Type 2 Diabetes Mellitus
Obesity
Kidney Diseases
Cardiovascular Diseases

Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform

Bikkul, M. U., Faragher, R. G. A., Worthington, G., Meinke, P., Kerr, A. R. W., Sammy, A., Riyahi, K., Horton, D., Schirmer, E. C., Hubank, M., Kill, I. R., Anderson, R. M., Slijepcevic, P., Makarov, E. & Bridger, J. M., 26 Nov 2018, In : Genes Chromosomes and Cancer. 58, 6, p. 341-356

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Progeria
Genomic Instability
Telomere
Protein Isoforms
Fibroblasts

Senescence in the aging process

Faragher, R., McArdle, A., Willows, A. & Ostler, E., 25 Jul 2017, In : F1000 Research. 6

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Phenotype
Transcriptome