Projects per year
Personal profile
Research interests
My research looks to understand the development, regulation and pathology of the musculoskeletal system, with a particular focus on understanding the molecular pathogenesis of osteoarthritis. My current research is funded by the Medical Research Council (>£2 million). My group consists of PDRAs Drs Lucie Bourne, Aikta Sharma and Lucinda Evans, and three PhD students (David Hughes, Rachel Lopera-Burgueno, Natalie Crump, Sophia Khan, Bew Promruk).
I currently sit on Veterinary Advisory Committee for the Horserace Betting Levy Board, and the Research Grant Assessment Panel for the Royal Osteoporosis Society. I am on the Editorial Board for the Journal of Endocrinology, the Journal of Molecular Endocrinology, and Frontiers in Endocrinology, Bone Research. I regularly review papers for a number of internationally-recoginsed journals, and have reviewed grants for a number of funding bodies including the MRC, BBSRC, & the Rosetrees Trust.. My research has featured as a number of press releases. I am currently the ECR Ambassador for the University of Brighton.
Scholarly biography
I completed my BSc in Anatomical Sciences at Bristol University in 2008. I then moved to the University of Edinburgh and was awarded my PhD in 2012, with a thesis that examined the role of Mepe in chondrocyte matrix mineralisation, under the direction of Prof. Colin Farquharson.
In 2012, I started my first postdoctoral position with Prof. Andy Pitsillides at the Royal Veterinary College, London. It was during this Arthritis Research UK funded post that my interest in osteoarthritis developed. In 2014, Imoved back to the University of Edinburgh to work on another Arthritis Research UK postdoctoral position looking at the subchondral bone in osteoarthritis. I was then awarded a Vice Chancellor's Fellowship at Edinburgh Napier University in 2017, before joining the University of Brighton as a Senior Lecturer in 2020.
Supervisory Interests
I currently supervise a dynamic team of PhD students and postdocs examining musculoskeletal health. My supervisory interests are:
- Osteoarthritis
- Secondary osteoporosis
- Musculoskeletal model development
- Imaging of the musculoskeletal system
I am always happy to hear from enthusiastic and motivated individuals who are looking to join our team.
Approach to teaching
I teach on various courses within the School of Applied Sciences and adopt a research-focused approach including discussing current and exciting literature, as well as my own research and that within SAS. I always strive to make my teaching as interactive as possible.
Education/Academic qualification
PhD, The role of Mepe in chondrocyte matrix mineralisation, University of Edinburgh
2008 → 2012
Bachelor, Anatomical Sciences, University of Bristol
2005 → 2008
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Collaborations and top research areas from the last five years
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BioGrOA: Imaging joint biomechanics in growth and osteoarthritis
1/03/22 → 30/09/25
Project: Research Councils / Government Depts.
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Ciliary IFT88 protects coordinated adolescent growth plate ossification from disruptive physiological mechanical forces
Coveney, C. R., Samvelyan, H. J., Miotla-Zarebska, J., Carnegie, J., Chang, E., Corrin, C. J., Coveney, T., Stott, B., Parisi, I., Duarte, C., Vincent, T. L., Staines, K. & Wann, A. K. T., 17 Jan 2022, In: Journal of Bone and Mineral Research. 37, 6, p. 1081-1096 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Increased PHOSPHO1 and alkaline phosphatase expression during the anabolic bone response to intermittent parathyroid hormone delivery
Houston, D. A., Stephen, L. A., Jayash, S. N., Myers, K., Little, K., Hopkinson, M., Pitsillides, A. A., MacRae, V. E., Millan, J. L., Staines, K. A. & Farquharson, C., 20 Dec 2022, In: Cell Biochemistry and Function. 41, 2, p. 189-201 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Increased PHOSPHO1 expression mediates cortical bone mineral density in renal osteodystrophy
Hsu, S-N., Stephen, L., Dillon, S., Milne, E., Javaheri, B., Pitsillides, A., Novak, A., Millan, JL., MacRae, VE., Staines, K. & Farquharson, C., 12 Aug 2022, In: Journal of Endocrinology. 254, 3, p. 153-167 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
PALMD regulates aortic valve calcification via altered glycolysis and NF-κB-mediated inflammation
Wang, S., Yu, H., Gao, J., Chen, J., He, P., Zhong, H., Tan, X., Staines, K. A., Macrae, V. E., Fu, X., Jiang, L. & Zhu, D., 1 Apr 2022, In: Journal of Biological Chemistry. 298, 5, 14 p., 101887.Research output: Contribution to journal › Article › peer-review
Open Access -
The role of accelerated growth plate fusion in the absence of SOCS2 on osteoarthritis vulnerability
Samvelyan, J., Huesca, C., Cui Lin, L., Farquharson, C. & Staines, K., 1 Mar 2022, In: Bone and Joint Research. 11, 3, p. 162-170 9 p.Research output: Contribution to journal › Article › peer-review
Open Access
Activities
- 3 Research degree
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PhD external examination
Katherine Staines (Examiner)
2021Activity: External examination and supervision › Research degree
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PhD external examination
Katherine Staines (Examiner)
2021Activity: External examination and supervision › Research degree
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PhD external examination
Katherine Staines (Examiner)
2018Activity: External examination and supervision › Research degree