Projects per year
Personal profile
Research interests
My research looks to understand the development, regulation and pathology of the musculoskeletal system, with a particular focus on understanding the molecular pathogenesis of osteoarthritis. My current research is funded by the Medical Research Council & Medical Research Scotland, and my group consists of a PDRA (Dr Jasmine Samvelyan), and three PhD students (David Hughes, Rachel Lopera-Burgueno, Lewis Hsu).
I am in the European Calcified Tissue Society (ECTS) Academy, and currently sit on the Editorial Board for the Journal of Endocrinology, the Journal of Molecular Endocrinology, BMC musculoskeletal disorders, and Frontiers in Endocrinology, Bone Research. I have reviewed papers for more than 35 different internationally-recoginsed journals, and has reviewed grants for a number of funding bodies including the Rosetrees Trust, the ECTS, and the Belgian Public Research Programme. My research has featured as a number of press releases.
Scholarly biography
I completed my BSc in Anatomical Sciences at Bristol University in 2008. I then moved to the University of Edinburgh and was awarded my PhD in 2012, with a thesis that examined the role of Mepe in chondrocyte matrix mineralisation, under the direction of Prof. Colin Farquharson.
In 2012, I started my first postdoctoral position with Prof. Andy Pitsillides at the Royal Veterinary College, London. It was during this Arthritis Research UK funded post that my interest in osteoarthritis developed. In 2014, Imoved back to the University of Edinburgh to work on another Arthritis Research UK postdoctoral position looking at the subchondral bone in osteoarthritis. I was then awarded a Vice Chancellor's Fellowship at Edinburgh Napier University in 2017, before joining the University of Brighton as a Senior Lecturer in 2020.
Supervisory Interests
I currently supervise a dynamic team of PhD students and postdocs examining musculoskeletal health. My supervisory interests are:
- Osteoarthritis
- Secondary osteoporosis
- Musculoskeletal model development
- Imaging of the musculoskeletal system
I am always happy to hear from enthusiastic and motivated individuals who are looking to join our team.
Approach to teaching
I teach on various courses with PABS and adopt a research-focused approach including discussing current and exciting literature, as well as my own research and that within PABS. I always strive to make my teaching as interactive as possible.
Education/Academic qualification
PhD, University of Edinburgh
2008 → 2012
Bachelor, University of Bristol
2005 → 2008
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Network
Projects
- 1 Active
Research output
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Conditional deletion of E11/Podoplanin in bone protects against ovariectomy-induced increases in osteoclast formation and activity
Staines, KA., Hopkinson, M., Dillon, S., Stephen, LA., Fleming, R., Sophocleous, A., Buttle, DJ., Pitsillides, AA. & Farquharson, C., 2 Jan 2020, In: Bioscience Reports. 40, 1, BSR20190329.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Life course longitudinal growth and risk of knee osteoarthritis at age 53 years: evidence from the 1946 British birth cohort study
Staines, K., Hardy, R., Samvelyan, H. J., Ward, K. A. & Cooper, R., 28 Dec 2020, In: Osteoarthritis and Cartilage.Research output: Contribution to journal › Article › peer-review
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Models of Osteoarthritis: Relevance and New Insights
Samvelyan, H. J., Hughes, D., Stevens, C. & Staines, K. A., 15 Feb 2020, In: Calcified Tissue International. 14 p.Research output: Contribution to journal › Literature review › peer-review
Open AccessFile -
The effects of exercise on Bone Mineral Density in Men: a protocol for a systematic review and meta-analysis of randomised controlled trials
Hamilton, B. R., Staines, K., Kelley, G., Kelley, K., Kohrt, W., Pitsiladis, Y. & Guppy, F. M., 19 May 2020Research output: Other contribution
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Zinc ameliorates human aortic valve calcification through GPR39 mediated ERK1/2 signalling pathway
Chen, Z., Gordillo-Martinez, F., Jiang, L., He, P., Hong, W., Wei, X., Staines, K., MacRae, V., Zhang, C., Yu, D., Fu, X. & Zhu, D., 7 Apr 2020, In: Cardiovascular Research. cvaa090.Research output: Contribution to journal › Article › peer-review