Personal profile

Research interests

I am currently an MRC funded Postdoctoral Research Fellow, working under the supervision of Dr Katherine Staines. My research interests lie within the musculoskeletal field and I am working on a number of projects in this area to understand how both bone and cartilage develop, function and undergo pathologies. 

Some of these projects include:

  • Identifying imaging biomarkers and assessing bone shape changes associated with osteoarthritis
  • Understanding how prenatal exposure to alcohol affects the skeleton later in life
  • Using RNAseq to idenitfy genes and pathways involved in physiological and injurious hydrstatic pressure on different cartilage models
  • Generating a double conditional knockout model to identify the roles of 2 phosphtases (alkaline phosphatase and Phospho1) specifically in the skeleton, to further understand how mineralisation occurs in this tissue

My previous experience and interests included understanding the differences between physiological and pathological mineralisation, for example within bone and during diseases such as vascular calcification.

Scholarly biography

Whilst completing a BSc (Hons) in Bioveterinary Sciences, I was fortunate to undertake a BBSRC funded experience placement at the Royal Veterinary College (RVC), London. After graduating in 2016, this became the basis for a PhD, under the supervision of Dr Isabel Orriss and Prof. Caroline Wheeler-Jones at the RVC. The thesis examined the differing calcification processes that are mediated by vascular smooth muscle cells and osteoblasts, and my PhD was awarded in 2020.  

During the troublesome times of the COVID pandemic, I undertook a short Visiting Research Fellow position at the University of Tromso, Norway, afterwards moving back to the RVC as a Senior Departmental Technician. Since then, I was able to find an exciting postdoc position and moved to the University of Brighton in October 2022 as a Postdoctoral Research Fellow in musculoskeletal aging. 

Education/Academic qualification

PhD, Comparison of the calcification processes mediated by osteoblasts and vascular smooth muscle cells, Royal Veterinary College University of London

4 Oct 201625 Sept 2020

Award Date: 25 Sept 2020

Bachelor, BSc (Hons) Bioveterinary Sciences

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