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Personal profile

Research interests

My research is in the field of biomaterials and tissue engineering with current focus on functional tissue and organ replacement strategies for kidney, liver and eye. I am interested in the replacement of tissues and organs using nanostructured adsorbent and smart polymer materials which can be modified with bioactive molecules to improve biocompatibility and functional performance. I am interested in better understanding the mechanisms that impact the cell-biomaterial interface and in the development of functional biomaterials for cell guidance, the control of infection, inflammation and oxidative stress. Such materials may be used for example, to improve the removal of inflammatory molecules and bacterial toxins which current limit the efficacy of dialysis for kidney and liver disease, as enterosorbents to slow the progression of liver disease, in the development of a wearable artificial kidney and in the development of corneal and lens replacement strategies for ophthalmic tissue engineering. Working within international networks of academic, clinical and industrial partners, I have led research projects funded by UK NIHR i4i (DART and ADEPT), EU FP7 IAPP (ACROBAT), EU Horizon 2020 (CARBALIVE), British Council GII (NOMAD) and UKRI MRC (MXene for accomodating IOL) funding streams.

Supervisory Interests

I supervise students in research areas related to biomedical materials and tissue engineering. I'm particularly interested in cell-biomaterial interactions and in strategies to understand changing tissue dynamics in disease and injury in order to optimise functional tissue repair and replacement.

Current PhD Students   

Natalia Noriega (2019-2022) Optoelectronic bionanomaterials for ophthalmic biosensing

Grace Cooksley (2019-2022) Optoelectronic nanomaterials to reduce the complications associated with cataract surgery

Wulan Koagouw (2017-2021)Integrative Assessment of Marine Pollution - Impact of Pharmaceuticals on Marine Bivalves

Neda Hedari (2017-2021)The role of senescence in bioartificial liver design

Emma Ward (2017-2021)A new class of two dimensional optoelectronic materials in accommodating intraocular lens design

Dr Vankata Avadhanam (2013 - current)Clinico-radiological study of OOKP lamina and development of a synthetic lamina

Tochukwu Ozulumba (2015 - 2019)Nanostructured scaffolds for remediation of environmental and biological tissue contaminants

Flavia Bonalumi (2017-2020)Engineering a bioartificial liver prototype using cell loaded macroporous hydrogel scaffolds

Previous PhD Students

Elsie Fok (2013) The development of advanced corneal epithelial stem cell delivery systems for the treatment of corneal epithelial defects 

Yishan Zheng  (2012) Hybrid filtration adsorbent systems for extracorporeal applications 

Education/Academic qualification

PhD, University of Brighton


Bachelor, Queen Mary University of London


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Research Output

Advances in Nanostructured Carbons for Biomedical Applications

Sandeman, S., Zheng, Y., Ingavle, G., Ozulumba, T., Howell, C. & Mikhalovsky, S., Jul 2020, Carbon Nanomaterials in Biomedicine and the Environment. Mansurov, Z. (ed.). Singapore, p. 271 286 p.

Research output: Chapter in Book/Conference proceeding with ISSN or ISBNChapter

  • Multiple drug delivery from the drug-implants-laden silicone contact lens: Addressing the issue of burst drug release

    Desai, A., Maulvi, F., Desai, D., Shukla, M., Ranch, K., Vyas, B., Shah, S., Sandeman, S. & Shah, D., 23 Mar 2020, In : Materials Science and Engineering: C. 110885.

    Research output: Contribution to journalArticle

  • Green synthesis of Pluronic stabilized reduced graphene oxide: Chemical and biological characterization

    Cherian, R., Sandeman, S., Ray, S., Savina, I., Ashtami, J. & Mohanan, PV., 25 Mar 2019, In : Colloids and Surfaces B: Biointerfaces. 179, 19, p. 94-106 13 p.

    Research output: Contribution to journalArticle

    Open Access
  • Plackett-Burman design for screening of critical variables and their effects on the optical transparency and swelling of gatifloxacin-Pluronic-loaded contact lens

    Maulvi, F. A., Parmar, R., Shukla, M., Desai, A., Desai, D., Ranch, K., Shah, S., Sandeman, S. & Shah, D., 5 Jun 2019, In : International Journal of Pharmaceutics. 566, p. 513-519 7 p.

    Research output: Contribution to journalArticle

  • Amine-Functionalized Electrically Conductive Core–Sheath MEH-PPV:PCL Electrospun Nanofibers for Enhanced Cell–Biomaterial Interactions

    Borah, R., Ingavle, G., Sandeman, S., Kumar, A. & Mikhalovsky, S., 14 Aug 2018, In : ACS Biomaterials Science & Engineering. 4, 9, p. 3327–3346 19 p.

    Research output: Contribution to journalArticle

    Open Access