Description
Surface-induced thrombosis and infection are two main complications which cause failure of medical devices. Device-related thrombosis is associated with activation of blood clotting and platelets adhesion and activation.
Infection of the implanted devices occurred as a result of bacteria adhesion to the biomaterial surface. A genuinely biocompatible polymer for bloodcontacting devices should have both antithrombotic and antibacterial functionalities as both types of complication lead to an increase in morbidity, extended hospital stay and mortality.
In order to prevent device-induced thrombosis and infection, novel dual function polymer materials - thromboresistant and antimicrobial, will be produced.
Infection of the implanted devices occurred as a result of bacteria adhesion to the biomaterial surface. A genuinely biocompatible polymer for bloodcontacting devices should have both antithrombotic and antibacterial functionalities as both types of complication lead to an increase in morbidity, extended hospital stay and mortality.
In order to prevent device-induced thrombosis and infection, novel dual function polymer materials - thromboresistant and antimicrobial, will be produced.
| Short title | DualFun |
|---|---|
| Status | Active |
| Effective start/end date | 18/09/17 → 17/09/19 |