Projects per year
Personal profile
Research interests
Dr Ananth Pannala FRSC is a pharmaceutical scientist with a keen interest and expertise in developing novel technologies for delivering therapeutically active molecules. His main research interests are:
- Encapsulation of therapeutically active molecules in polylactic acid nanoparticles for pulmonary drug delivery
- pH sensitive release of therapeutically active molecules from biodegradable microparticles for oral drug delivery
- Development of water soluble complexes with therapeutically active molecules for oral drug delivery
- Targeted drug delivery to the kidney for the treatment of acute kidney injury
- Role of oxidative and nitrative stress in health and disease and the efficacy of antioxidants in such conditions
Approach to teaching
My approach to teaching is based on "how would I like to learn the material?". To this effect I had used different teaching and learning approaches such as blended learning, flipped classroom and pedagogic and andragogic approach for module development, teaching, learning and assessment.
The main approach to teaching, however, revolves around practical based application of knowledge. I strongly believe that applying the theoretical knowledge in a practical manner will help in better understanding of the basic concepts. I encourage students to think about the theory and come up with practical solutions.
Scholarly biography
Dr Ananth Pannala FRSC is a Principal Lecturer in Pharmaceutics in the School of Pharmacy and Biomolecular Sciences, University of Brighton. He is the lead for the Biomaterials and Medical Devices and Drug Delivery Research and Enterprise Group.
He is a pharmacist by qualification and his research is predominantly in health and pharmaceutical sciences. His work experience includes both academic and the pharmaceutical industry research fields.
Education/Academic qualification
PhD, Peroxynitrite induced oxidative modification of low density lipoprotein, King's College London
Award Date: 27 Oct 1997
Master, Synthesis and evaluation of curcumin hindered phenol for enhanced antioxidant and antiinflammatory activity, Manipal Academy of Higher Education
Award Date: 30 Jun 1993
External positions
Visiting Professor, Manipal Academy of Higher Education
Keywords
- RS Pharmacy and materia medica
- Nanoparticle
- Drug delivery
- Antioxidants
- Microparticles
- Biomaterials
- Polylactic acid
- Pulmonary drug delivery
- liposomes
- iron chelators
- acute kidney injury
- gold nanoparticles
- spray drying
- Mathematical modelling
- Chromatography
- Spectroscopy
- SEM
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Collaborations and top research areas from the last five years
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NGSSM: Next generation spray simulation model
Rybdylova, O., Begg, S., Pannala, A. & Stafford, C.
1/02/21 → 31/01/26
Project: Research Councils / Government Depts.
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Bioengineering controlled release from contact lens hydrogels
Lloyd, A., Sandeman, S., Pannala, A. & Hawthorne, D.
1/07/19 → 29/02/24
Project: Industry
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The formulation of curcumin preparations with enhanced bioavailability for manufacturing in Vietnam
Smart, J. & Pannala, A.
1/04/16 → 30/09/18
Project: Charities
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Engineering artesunate-loaded micelles using spray drying for pulmonary drug delivery
Somavarapu, S., Sornsute, A., Trill, J., Abdelhakim, H., Goonatilaka, D., Pannala, A. & Taylor, K., 12 Jun 2023, In: Journal of Drug Delivery Science and Technology. 86, 10 p., 104641.Research output: Contribution to journal › Article › peer-review
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Topical Micro-Emulsion of 5-Fluorouracil by a Twin Screw Processor-Based Novel Continuous Manufacturing Process for the Treatment of Skin Cancer: Preparation and In Vitro and In Vivo Evaluations
Nikam, A. N., Jacob, A., Raychaudhuri, R., Fernandes, G., Pandey, A., Rao, V., Ahmad, S. F., Pannala, A. S. & Mutalik, S., 22 Aug 2023, In: Pharmaceutics. 15, 9, 18 p., 2175.Research output: Contribution to journal › Article › peer-review
Open Access -
Increasing Cellular Uptake and Permeation of Curcumin Using a Novel Polymer-Surfactant Formulation
Liu, Z., Lansley, A., Duong, T. N., Smart, J. & Pannala, A., 23 Nov 2022, In: Biomolecules. 12, 12, 1739.Research output: Contribution to journal › Article › peer-review
Open Access -
Protective Effects of Resveratrol Encapsulated in Liposomes or PLA Nanoparticles against Oxidative Stress in NRK-52E Cells
Layas, K., Chatterjee, C. & Pannala, A., 9 Nov 2022, In: Nanoparticle. 3, 2, 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Sustained and targeted delivery of hydrophilic drug compounds: A review of existing and novel technologies from bench to bedside
Hawthorne, D., Pannala, A., Sandeman, S. & Lloyd, A., 4 Nov 2022, In: Journal of Drug Delivery Science and Technology. 78, 103936.Research output: Contribution to journal › Article › peer-review
Open Access