Projects per year
Personal profile
Research interests
My main area of research interest is in the polymer materials and development of novel advanced materials for biomedical and environmental applications. My research group is a multi-disciplinary team with research interests in the development and characterisation of novel porous materials, hydrogels, (nano) composites and nanoparticle based materials. I focus on the development of functional materials for applications in the wound healing, tissue engineering, drug delivery and removing contaminants from water.
Specifically, my research areas include
- Synthesis of functional porous polymer gels, hybrid polymer-inorganic and nanocomposite materials
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Characterisation of soft porous materials
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Development of smart polymer systems
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Development of drug delivery systems
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Development of novel materials for contaminated water remediation.
Accepting PhD students
Collaborators Dr T. Abdullin, Laboratory of Bioactive Polymers and Peptides, https://kpfu.ru/eng/strau/laboratories/bioactive-polymers-and-peptides
Dr M Alavijeh, Pharmidex https://www.pharmidex.com
Previous research projects:
Development of the flow through bioreactor of 3D-structured bacteria for biodegradation of aromatic chloro-derivatives from contaminated water. (H2020-MSCA-IF grant)
Water and soil clean-up from mixed contaminants (FP7-PEOPLE-IAPP, WaSClean project).
Investigation of neurotoxicity and oxidative stress of PEGylated nanographeneusing rat pheochromocytoma (PC-12) neuronal cell lines (Commonwealth scholarship).
Nanomaterials for practical use in remediation: Case study of mercury contamination in the lake Bylkyldak (The Ministry of Education and Science of the Republic of Kazakhstan).
Immobilized noble metal nanoparticles as efficient flow through catalyst for “green” decomposition of chlorinated aromatic compounds (British Council Newton grant).
Controlled production and chemical modification of a variety of novel-carbons for specific end applications into the bio-organic field (FP7-PEOPLE-IRSES staff exchange programme ENSOR).
Novel smart materials for biomedical application (FP7-PEOPLE-RG grant - Bio-Smart).
Developing and evaluation of a quantitative imaging technique for assessment of nanoparticle drug delivery across the blood-brain barrier: Application for brain cancer therapeutics (FP7-PEOPLE-IAPP grant, OncoNanoBBB).
Studying adsorption of proteins on the carbon based materials (Institut Laue-Langevin (ILL) research grant).
Developing novel nanocomposite materials for the water clean-up (FP7-PEOPLE-IEF. MacroClean)
Development and manufacture of permeable composite filters for environment application (FP7-PEOPLE-IAPP, CARBOSORB).
Tissue engineering materials based on macroporous cryogels and non-viral delivery systems, growth factors: the development and testing in peripheral nerve injury and therapeutic angiogenesis (Russian Federal Programme grant).
Supervisory Interests
Projects on developing polymer materials, hydrogel, nanocomposites for biomedical and environmental applications. Particular interest in biomaterials, drug delivery systems, nanoparticles as catalyst and antibacterial agents, materials/methods for water decontamination.
Education/Academic qualification
PhD, Composite poly (vinyl alcohol) cryogels: preparation, influence of dispersed phase properties and applications., RAS - A.N. Nesmeyanov Institute of Organoelement Compounds
1 Sept 1999 → 1 Nov 2003
Award Date: 1 Nov 2003
Keywords
- QD Chemistry
- Synthesis of functional porous polymer gels, hybrid polymer-inorganic and nanocomposite materials, smart polymer systems, biomaterials, drug delivery systems, nanoparticles, characterisation of soft porous materials, novel technologies for contaminated soil and water remediation
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Collaborations and top research areas from the last five years
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Bioartificial interventions for organ senescence: Understanding and preventing senescence induced by liver toxins (SILT) in hepatocytes
Faragher, R. (PI), Sandeman, S. (CoI) & Savina, I. (CoI)
1/11/23 → 31/08/25
Project: Research Councils / Government Depts.
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Novel catalytic systems for disposal of the halogenated pharmaceutical and personal care products
Savina, I. (PI)
4/11/19 → 3/11/22
Project: Research Councils / Government Depts.
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GLIOMA: H2020-MSCA-Individual Fellowship - Targeting Glioblastoma using Combinatorial Therapeutic Nanovaccine
Savina, I. (PI), Raveendran, S. (CoI), Alavijeh, M. (CoI) & Shevchenko, R. (CoI)
2/10/17 → 1/10/19
Project: Grant
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Amphiphilic polymer-based enhancers for local drugs delivery to the inner ear
Lukashkin, A. (PI), Savina, I. (CoI), Smart, J. (CoI) & Lukashkina, V. (CoI)
1/09/16 → 31/07/18
Project: EU / International
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MXene-Reinforced Composite Cryogel Scaffold for Neural Tissue Repair
Zoughaib, M., Avdokushina, S. & Savina, I. N., 22 Jan 2025, In: Molecules. 30, 3, 15 p., 479.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Combinatorial Therapy: Targeting CD133+ Glioma Stem-like Cells with a Polysaccharide–Prodrug Complex Functionalised Gold Nanocages
Raveendran, S., Giram, A., Elmi, M., Ray, S., Ireson, C., Alavijeh, M. & Savina, I. N., 23 Apr 2024, In: Biomedicines. 12, 5, 19 p., 934.Research output: Contribution to journal › Article › peer-review
Open Access -
Cryogels with Noble Metal Nanoparticles as Catalyst for “Green” Decomposition of Chlorophenols
Berillo, D. A. & Savina, I. N., 2 Jan 2023, In: Inorganics. 11, 1, 21 p., 23.Research output: Contribution to journal › Article › peer-review
Open Access -
Introduction to the RSC Advances themed collection on Nanomaterials in drug delivery
Santos, H. A. & Savina, I. N., 11 Jan 2023, In: RSC Advances. 13, 3, p. 1933-1934 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Macroporous Cryogel-Based Systems for Water Treatment Applications and Safety: Nanocomposite-Based Cryogels and Bacteria-Based Bioreactors
Savina, I., Berillo, D. & Otero-González, L., 9 May 2023, Biomedical Applications and Toxicity of Nanomaterials. Springer, p. 1-49 49 p.Research output: Chapter in Book/Conference proceeding with ISSN or ISBN › Chapter › peer-review
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CRC Press, Taylor & Francis Group (Publisher)
Savina, I. (Reviewer)
2021 → 2022Activity: Publication peer-review and editorial work › Editorial work
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RSC Advances (Journal)
Savina, I. (Reviewer)
2021 → 2022Activity: Publication peer-review and editorial work › Editorial work
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MDPI, Molecules, Guest Editor of Special Issue "Porous Materials" (Publisher)
Savina, I. (Reviewer)
1 Mar 2020Activity: Publication peer-review and editorial work › Editorial work
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Nature Communications (Journal)
Savina, I. (Reviewer)
2019Activity: Publication peer-review and editorial work › Publication Peer-review
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