Synthesis and properties of (6,7-dimethoxy-4-coumaryl)alanine: A fluorescent peptide label

Fiona Bennett, David J. Barlow, Alexander N.O. Dodoo, Robert C. Hider, Alison Lansley, Jayne M. Lawrence, Christopher Marriott

Research output: Contribution to journalArticle

Abstract

The synthesis of racemic andl-(6,7-dimethoxy-4-coumaryl)alanine (Dmca) is described and some spectral and physicochemical properties are reported. The utility of Dmca as a highly sensitive and specific label for the quantitative detection of synthetic peptides in HPLC and in minimal essential media (MEM) is also described.
Original languageEnglish
Pages (from-to)15-23
Number of pages9
JournalAnalytical Biochemistry
Volume270
Issue number1
DOIs
Publication statusPublished - 15 May 1999

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    Bennett, F., Barlow, D. J., Dodoo, A. N. O., Hider, R. C., Lansley, A., Lawrence, J. M., & Marriott, C. (1999). Synthesis and properties of (6,7-dimethoxy-4-coumaryl)alanine: A fluorescent peptide label. Analytical Biochemistry, 270(1), 15-23. https://doi.org/10.1006/abio.1999.4081