L-(6,7-dimethoxy-4-coumaryl) alanine: an intrinsic probe for the labelling of peptides

Fiona Bennett, David J. Barlow, Alexander N.O. Dodoo, Robert C. Hider, Alison Lansley, Jayne M. Lawrence, Christopher Marriott

Research output: Contribution to journalArticlepeer-review


The asymmetric synthesis, spectral properties and incorporation into solid phase peptide synthesis are described for L-(6,7-dimethoxy-4-coumaryl)alanine (Dca). Dca has great utility as a specific and highly sensitive intrinsic probe for fluorescence labelling and quantitation of peptides and proteins.
Original languageEnglish
Pages (from-to)7449-7452
Number of pages4
JournalTetrahedron Letters
Issue number42
Publication statusPublished - 20 Oct 1997


Dive into the research topics of 'L-(6,7-dimethoxy-4-coumaryl) alanine: an intrinsic probe for the labelling of peptides'. Together they form a unique fingerprint.

Cite this