L-(6,7-dimethoxy-4-coumaryl) alanine: an intrinsic probe for the labelling of peptides

Fiona Bennett, David J. Barlow, Alexander N.O. Dodoo, Robert C. Hider, Alison Lansley, Jayne M. Lawrence, Christopher Marriott

Research output: Contribution to journalArticle

Abstract

The asymmetric synthesis, spectral properties and incorporation into solid phase peptide synthesis are described for L-(6,7-dimethoxy-4-coumaryl)alanine (Dca). Dca has great utility as a specific and highly sensitive intrinsic probe for fluorescence labelling and quantitation of peptides and proteins.
Original languageEnglish
Pages (from-to)7449-7452
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number42
DOIs
Publication statusPublished - 20 Oct 1997

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    Bennett, F., Barlow, D. J., Dodoo, A. N. O., Hider, R. C., Lansley, A., Lawrence, J. M., & Marriott, C. (1997). L-(6,7-dimethoxy-4-coumaryl) alanine: an intrinsic probe for the labelling of peptides. Tetrahedron Letters, 38(42), 7449-7452. https://doi.org/10.1016/S0040-4039(97)01753-X