ConStruct.1.r is an R Script that estimates the relative contributions of consanguinity and population substructure to excess homozygosity. ConStruct.1.r also offers the option of simulating data with a given FST and magnitude of consanguinity, incorporating a user-specified number of loci, number of alleles and population size. The method seems robust when population sizes are above 200 and individuals are genotyped at greater than 10 loci.
|Publication status||Published - 13 Jan 2016|
Bibliographical note© 2016 The Author(s). This open access article is distributed under a Creative Commons Attribution (CC-BY) 4.0 license.
- R Script
- population substructure
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- School of Applied Sciences - Senior Lecturer
- Ecology, Conservation and Society Research and Enterprise Group