Baseline haematological and biochemical reference values for healthy male adults from Mali

Serena Vita, Alessandro Miglietta, Maurizio Lopalco , Nadia Terrazzini, Valeria Sargentini , Eleonora Cella , Alessandra Bachetoni , Giordano Dicuonzo , Silvia Angeletti , Massimo Ciccozzi , Giancarlo Ceccarelli

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: Haematological reference values are very important for diagnostic orientation and treatment decision. The aim of this study was to establish haematological reference values for Malian healthy adults.
Methods: A cross-sectional study including 161 male Malians aged between 19 and 54 years old was performed. Median and reference ranges were calculated for haematological and biochemical parameters. Parametric student’s t-test was used to determine any statistically significant differences by age, smoker status, body mass index (BMI) and occupation. Ranges were further compared with those reported for other African , Afro-American and Caucasian populations.
Results: Increased levels of MCV, MCH, PLT and EOS were found in younger Malians who had abnormal BMI and altered platelets parameters . Notably, significantly lower eosinophil and monocyte counts were observed in Malians compared to Europeans The smoking status did not seem to directly affect RIs.
Conclusions: This is the first study to determine normal laboratory parameters in Malian adult males. Our results underscore the necessity of establishing region-specific clinical reference ranges that would allow clinicians and practitioners to manage laboratory tests, diagnosis and therapies. These data are useful not only for the management of patients in Mali, but also to support European and American clinicians in the health management of asylum seekers and migrants from Mali.
Original languageEnglish
Journal Pan African Medical Journal
Volume32
Issue number5
DOIs
Publication statusPublished - 4 Jan 2019

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Mali
Reference Values
Body Mass Index
Refugees
Clinical Laboratory Techniques
Occupations
Eosinophils
African Americans
Monocytes
Blood Platelets
Cross-Sectional Studies
Smoking
Students
Health
Therapeutics
Population

Bibliographical note

© Serena Vita et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Keywords

  • Haematological reference range
  • Malian adults
  • sub-saharan migrants

Cite this

Vita, S., Miglietta, A., Lopalco , M., Terrazzini, N., Sargentini , V., Cella , E., ... Ceccarelli , G. (2019). Baseline haematological and biochemical reference values for healthy male adults from Mali. 32(5). https://doi.org/10.11604/pamj.2019.32.5.12797
Vita, Serena ; Miglietta, Alessandro ; Lopalco , Maurizio ; Terrazzini, Nadia ; Sargentini , Valeria ; Cella , Eleonora ; Bachetoni , Alessandra ; Dicuonzo , Giordano ; Angeletti , Silvia ; Ciccozzi , Massimo ; Ceccarelli , Giancarlo. / Baseline haematological and biochemical reference values for healthy male adults from Mali. 2019 ; Vol. 32, No. 5.
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abstract = "Background: Haematological reference values are very important for diagnostic orientation and treatment decision. The aim of this study was to establish haematological reference values for Malian healthy adults.Methods: A cross-sectional study including 161 male Malians aged between 19 and 54 years old was performed. Median and reference ranges were calculated for haematological and biochemical parameters. Parametric student’s t-test was used to determine any statistically significant differences by age, smoker status, body mass index (BMI) and occupation. Ranges were further compared with those reported for other African , Afro-American and Caucasian populations. Results: Increased levels of MCV, MCH, PLT and EOS were found in younger Malians who had abnormal BMI and altered platelets parameters . Notably, significantly lower eosinophil and monocyte counts were observed in Malians compared to Europeans The smoking status did not seem to directly affect RIs. Conclusions: This is the first study to determine normal laboratory parameters in Malian adult males. Our results underscore the necessity of establishing region-specific clinical reference ranges that would allow clinicians and practitioners to manage laboratory tests, diagnosis and therapies. These data are useful not only for the management of patients in Mali, but also to support European and American clinicians in the health management of asylum seekers and migrants from Mali.",
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Vita, S, Miglietta, A, Lopalco , M, Terrazzini, N, Sargentini , V, Cella , E, Bachetoni , A, Dicuonzo , G, Angeletti , S, Ciccozzi , M & Ceccarelli , G 2019, 'Baseline haematological and biochemical reference values for healthy male adults from Mali' vol. 32, no. 5. https://doi.org/10.11604/pamj.2019.32.5.12797

Baseline haematological and biochemical reference values for healthy male adults from Mali. / Vita, Serena; Miglietta, Alessandro; Lopalco , Maurizio; Terrazzini, Nadia; Sargentini , Valeria; Cella , Eleonora; Bachetoni , Alessandra; Dicuonzo , Giordano; Angeletti , Silvia; Ciccozzi , Massimo; Ceccarelli , Giancarlo.

Vol. 32, No. 5, 04.01.2019.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Baseline haematological and biochemical reference values for healthy male adults from Mali

AU - Vita, Serena

AU - Miglietta, Alessandro

AU - Lopalco , Maurizio

AU - Terrazzini, Nadia

AU - Sargentini , Valeria

AU - Cella , Eleonora

AU - Bachetoni , Alessandra

AU - Dicuonzo , Giordano

AU - Angeletti , Silvia

AU - Ciccozzi , Massimo

AU - Ceccarelli , Giancarlo

N1 - © Serena Vita et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PY - 2019/1/4

Y1 - 2019/1/4

N2 - Background: Haematological reference values are very important for diagnostic orientation and treatment decision. The aim of this study was to establish haematological reference values for Malian healthy adults.Methods: A cross-sectional study including 161 male Malians aged between 19 and 54 years old was performed. Median and reference ranges were calculated for haematological and biochemical parameters. Parametric student’s t-test was used to determine any statistically significant differences by age, smoker status, body mass index (BMI) and occupation. Ranges were further compared with those reported for other African , Afro-American and Caucasian populations. Results: Increased levels of MCV, MCH, PLT and EOS were found in younger Malians who had abnormal BMI and altered platelets parameters . Notably, significantly lower eosinophil and monocyte counts were observed in Malians compared to Europeans The smoking status did not seem to directly affect RIs. Conclusions: This is the first study to determine normal laboratory parameters in Malian adult males. Our results underscore the necessity of establishing region-specific clinical reference ranges that would allow clinicians and practitioners to manage laboratory tests, diagnosis and therapies. These data are useful not only for the management of patients in Mali, but also to support European and American clinicians in the health management of asylum seekers and migrants from Mali.

AB - Background: Haematological reference values are very important for diagnostic orientation and treatment decision. The aim of this study was to establish haematological reference values for Malian healthy adults.Methods: A cross-sectional study including 161 male Malians aged between 19 and 54 years old was performed. Median and reference ranges were calculated for haematological and biochemical parameters. Parametric student’s t-test was used to determine any statistically significant differences by age, smoker status, body mass index (BMI) and occupation. Ranges were further compared with those reported for other African , Afro-American and Caucasian populations. Results: Increased levels of MCV, MCH, PLT and EOS were found in younger Malians who had abnormal BMI and altered platelets parameters . Notably, significantly lower eosinophil and monocyte counts were observed in Malians compared to Europeans The smoking status did not seem to directly affect RIs. Conclusions: This is the first study to determine normal laboratory parameters in Malian adult males. Our results underscore the necessity of establishing region-specific clinical reference ranges that would allow clinicians and practitioners to manage laboratory tests, diagnosis and therapies. These data are useful not only for the management of patients in Mali, but also to support European and American clinicians in the health management of asylum seekers and migrants from Mali.

KW - Haematological reference range

KW - Malian adults

KW - sub-saharan migrants

U2 - 10.11604/pamj.2019.32.5.12797

DO - 10.11604/pamj.2019.32.5.12797

M3 - Article

VL - 32

IS - 5

ER -