Baseline haematological and biochemical reference values for healthy male adults from Mali

Serena Vita, Alessandro Miglietta, Maurizio Lopalco , Nadia Terrazzini, Valeria Sargentini , Eleonora Cella , Alessandra Bachetoni , Giordano Dicuonzo , Silvia Angeletti , Massimo Ciccozzi , Giancarlo Ceccarelli

    Research output: Contribution to journalArticlepeer-review


    Introduction: Haematological reference values are very important for diagnostic orientation and treatment decision. The aim of this study was to establish haematological reference values for Malian healthy adults. Methods: A cross-sectional study including 161 male Malians aged between 19 and 54 years old was performed. Median and reference ranges were calculated for haematological and biochemical parameters. Parametric student's t-test was used to determine any statistically significant differences by age, smoker status, body mass index (BMI) and occupation. Ranges were further compared with those reported for other African, Afro-American and Caucasian populations. Results: Increased levels of MCV, MCH, PLT and EOS were found in younger Malians who had abnormal BMI and altered platelets parameters. Notably, significantly lower eosinophil and monocyte counts were observed in Malians compared to Europeans The smoking status did not seem to directly affect RIs. Conclusion: This is the first study to determine normal laboratory parameters in Malian adult males. Our results underscore the necessity of establishing region-specific clinical reference ranges that would allow clinicians and practitioners to manage laboratory tests, diagnosis and therapies. These data are useful not only for the management of patients in Mali, but also to support European and American clinicians in the health management of asylum seekers and migrants from Mali.

    Original languageEnglish
    Journal Pan African Medical Journal
    Issue number5
    Publication statusPublished - 4 Jan 2019

    Bibliographical note

    © Serena Vita et al. The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


    • Haematological reference range
    • Malian adults
    • sub-saharan migrants
    • Sub-saharan migrants


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