Allowing for within-subpopulation inbreeding in forensic match probabilities

K.L. Ayres, Andrew Overall

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The importance of allowing for recent shared ancestry when calculating forensic match probabilities has been recognised for some time. Within-subpopulation inbreeding will also affect the match probability, and ignoring these effects can lead to an overstatement of the strength of the DNA evidence against a defendant. However, inbreeding can be readily accounted for in match probabilities by incorporating the inbreeding coefficient F into calculations. We derive the IS necessary formulae, and demonstrate the effect of including F (in addition to F ) in the IS ST equations.
Original languageEnglish
Pages (from-to)207-216
Number of pages10
JournalForensic Science International
Volume103
Issue number3
Publication statusPublished - 9 Sep 1999

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Keywords

  • DNA profiling
  • F-ST
  • F-IS
  • inbreeding coefficient
  • forensic identification
  • population genetics

Cite this

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abstract = "The importance of allowing for recent shared ancestry when calculating forensic match probabilities has been recognised for some time. Within-subpopulation inbreeding will also affect the match probability, and ignoring these effects can lead to an overstatement of the strength of the DNA evidence against a defendant. However, inbreeding can be readily accounted for in match probabilities by incorporating the inbreeding coefficient F into calculations. We derive the IS necessary formulae, and demonstrate the effect of including F (in addition to F ) in the IS ST equations.",
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Allowing for within-subpopulation inbreeding in forensic match probabilities. / Ayres, K.L.; Overall, Andrew.

In: Forensic Science International, Vol. 103, No. 3, 09.09.1999, p. 207-216.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Allowing for within-subpopulation inbreeding in forensic match probabilities

AU - Ayres, K.L.

AU - Overall, Andrew

PY - 1999/9/9

Y1 - 1999/9/9

N2 - The importance of allowing for recent shared ancestry when calculating forensic match probabilities has been recognised for some time. Within-subpopulation inbreeding will also affect the match probability, and ignoring these effects can lead to an overstatement of the strength of the DNA evidence against a defendant. However, inbreeding can be readily accounted for in match probabilities by incorporating the inbreeding coefficient F into calculations. We derive the IS necessary formulae, and demonstrate the effect of including F (in addition to F ) in the IS ST equations.

AB - The importance of allowing for recent shared ancestry when calculating forensic match probabilities has been recognised for some time. Within-subpopulation inbreeding will also affect the match probability, and ignoring these effects can lead to an overstatement of the strength of the DNA evidence against a defendant. However, inbreeding can be readily accounted for in match probabilities by incorporating the inbreeding coefficient F into calculations. We derive the IS necessary formulae, and demonstrate the effect of including F (in addition to F ) in the IS ST equations.

KW - DNA profiling

KW - F-ST

KW - F-IS

KW - inbreeding coefficient

KW - forensic identification

KW - population genetics

M3 - Article

VL - 103

SP - 207

EP - 216

JO - Forensic Science International

JF - Forensic Science International

SN - 0379-0738

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