Plume image profiling of UV laser desorbed biomolecules

T. L. Merrigan, C. A. Hunniford, D. J. Timson, M. Catney, R. W. McCullough

    Research output: Contribution to journalArticlepeer-review


    An experimental system, based upon the techniques of UV and IR laser desorption with time of flight mass spectrometry, has been constructed to enable the production and characterization of neutral biomolecular targets. The feasibility of the laser desorption technique for the purpose of radiation interaction experiments is investigated here. Fluorescent dye tagging and laser induced fluorescence imaging has been used to help characterize the laser produced plumes of biomolecules revealing their spatial density profiles and temporal evolution. Peak target thicknesses of 2 × 1012 molecules cm-2 were obtained 30μs after laser desorption.

    Original languageEnglish
    Pages (from-to)176-181
    Number of pages6
    JournalAIP Conference Proceedings
    Publication statusPublished - 1 Dec 2008
    Event5th International Conference on Radiation Damage in Biomolecular Systems, RADAM 2008 - Debrecen, Hungary
    Duration: 13 Jun 200815 Jun 2008


    • Biomolecules
    • Laser desorption
    • Mass spectrometry


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