PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress

Afreen Haider; Yu-Chen Wei; Koini Lim; Antonio D. Barbosa; Che-Hsiung Liu; Ursula Weber; Marek Mlodzik; Kadri Oras; Simon Collier; M. Mahmood Hussain; Liang Dong; Satish Patel; Anna Alvarez-Guaita; Vladimir Saudek; Benjamin J. Jenkins; Albert Koulman; Marcus Dymond; Roger C. Hardie; Symeon Siniossoglou; David B. Savage

doi:10.1016/j.devcel.2018.04.012

PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress

Afreen Haider, Yu-Chen Wei, Koini Lim, Antonio D. Barbosa, Che-Hsiung Liu, Ursula Weber, Marek Mlodzik, Kadri Oras, Simon Collier, M. Mahmood Hussain, Liang Dong, Satish Patel, Anna Alvarez-Guaita, Vladimir Saudek, Benjamin J. Jenkins, Albert Koulman, Marcus Dymond, Roger C. Hardie, Symeon Siniossoglou, David B. Savage

Research output: Contribution to journal › Article

Original language	English
Pages (from-to)	481-495
Number of pages	15
Journal	Developmental Cell
Volume	45
Issue number	4
DOIs	https://doi.org/10.1016/j.devcel.2018.04.012
Publication status	Published - 10 May 2018

Bibliographical note

Keywords

phosphatidylcholine
Kennedy pathway
CCT
PCYT1A
lipidomics
stored curvature elastic stress

Access to Document

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Marcus Dymond
- M.Dymond@brighton.ac.uk
- School of Pharmacy and Biomolecular Sci - Principal Lecturer
- Centre for Stress and Age-Related Disease
- Chemistry Research and Enterprise Group
Person: Academic

Cite this

Haider, A., Wei, Y-C., Lim, K., Barbosa, A. D., Liu, C-H., Weber, U., Mlodzik, M., Oras, K., Collier, S., Hussain, M. M., Dong, L., Patel, S., Alvarez-Guaita, A., Saudek, V., Jenkins, B. J., Koulman, A., Dymond, M., Hardie, R. C., Siniossoglou, S., & Savage, D. B. (2018). PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress. Developmental Cell, 45(4), 481-495. https://doi.org/10.1016/j.devcel.2018.04.012

Haider, Afreen ; Wei, Yu-Chen ; Lim, Koini ; Barbosa, Antonio D. ; Liu, Che-Hsiung ; Weber, Ursula ; Mlodzik, Marek ; Oras, Kadri ; Collier, Simon ; Hussain, M. Mahmood ; Dong, Liang ; Patel, Satish ; Alvarez-Guaita, Anna ; Saudek, Vladimir ; Jenkins, Benjamin J. ; Koulman, Albert ; Dymond, Marcus ; Hardie, Roger C. ; Siniossoglou, Symeon ; Savage, David B. / PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress. In: Developmental Cell. 2018 ; Vol. 45, No. 4. pp. 481-495.

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title = "PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress",

keywords = "phosphatidylcholine, Kennedy pathway, CCT, PCYT1A, lipidomics, stored curvature elastic stress",

author = "Afreen Haider and Yu-Chen Wei and Koini Lim and Barbosa, {Antonio D.} and Che-Hsiung Liu and Ursula Weber and Marek Mlodzik and Kadri Oras and Simon Collier and Hussain, {M. Mahmood} and Liang Dong and Satish Patel and Anna Alvarez-Guaita and Vladimir Saudek and Jenkins, {Benjamin J.} and Albert Koulman and Marcus Dymond and Hardie, {Roger C.} and Symeon Siniossoglou and Savage, {David B.}",

note = "{\textcopyright} 2018 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).",

year = "2018",

month = may,

day = "10",

doi = "10.1016/j.devcel.2018.04.012",

language = "English",

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Haider, A, Wei, Y-C, Lim, K, Barbosa, AD, Liu, C-H, Weber, U, Mlodzik, M, Oras, K, Collier, S, Hussain, MM, Dong, L, Patel, S, Alvarez-Guaita, A, Saudek, V, Jenkins, BJ, Koulman, A, Dymond, M, Hardie, RC, Siniossoglou, S & Savage, DB 2018, 'PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress', Developmental Cell, vol. 45, no. 4, pp. 481-495. https://doi.org/10.1016/j.devcel.2018.04.012

PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress. / Haider, Afreen; Wei, Yu-Chen; Lim, Koini; Barbosa, Antonio D.; Liu, Che-Hsiung; Weber, Ursula; Mlodzik, Marek; Oras, Kadri; Collier, Simon; Hussain, M. Mahmood; Dong, Liang; Patel, Satish; Alvarez-Guaita, Anna; Saudek, Vladimir; Jenkins, Benjamin J.; Koulman, Albert; Dymond, Marcus; Hardie, Roger C.; Siniossoglou, Symeon; Savage, David B.

In: Developmental Cell, Vol. 45, No. 4, 10.05.2018, p. 481-495.

Research output: Contribution to journal › Article

TY - JOUR

T1 - PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress

AU - Haider, Afreen

AU - Wei, Yu-Chen

AU - Lim, Koini

AU - Barbosa, Antonio D.

AU - Liu, Che-Hsiung

AU - Weber, Ursula

AU - Mlodzik, Marek

AU - Oras, Kadri

AU - Collier, Simon

AU - Hussain, M. Mahmood

AU - Dong, Liang

AU - Patel, Satish

AU - Alvarez-Guaita, Anna

AU - Saudek, Vladimir

AU - Jenkins, Benjamin J.

AU - Koulman, Albert

AU - Dymond, Marcus

AU - Hardie, Roger C.

AU - Siniossoglou, Symeon

AU - Savage, David B.

PY - 2018/5/10

Y1 - 2018/5/10

KW - phosphatidylcholine

KW - Kennedy pathway

KW - CCT

KW - PCYT1A

KW - lipidomics

KW - stored curvature elastic stress

U2 - 10.1016/j.devcel.2018.04.012

DO - 10.1016/j.devcel.2018.04.012

M3 - Article

VL - 45

SP - 481

EP - 495

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 4

ER -