Green' and sustainable halogenation processes

Graham Pattison

Research output: Chapter in Book/Conference proceeding with ISSN or ISBNChapterpeer-review


Halogen atoms have proven both to be some of the most useful functionality available to medicinal chemists, both as handles for further derivatisation and diversification and also due to the beneficial properties they, particularly fluorine, can impart on drug candidates. However, many reagents for halogenation can be potentially dangerous, difficult to handle and can have negative environmental impacts. This short chapter highlights recent approaches to avoid such difficult halogenation reagents and replace them with safer, more sustainable alternatives.

Original languageEnglish
Title of host publicationMicrowave-Assisted Polymerization
PublisherRoyal Society of Chemistry
Number of pages15
Publication statusPublished - 1 Jan 2016

Publication series

NameRSC Green Chemistry
ISSN (Print)1757-7039
ISSN (Electronic)1757-7047


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