Development of an in-vitro model for oral biofilm studies

O. Adenuga; K. Charman; D. Churchley; G. Rees; C. Parkinson; Lara-Marie Barnes

Development of an in-vitro model for oral biofilm studies

O. Adenuga, K. Charman, D. Churchley, G. Rees, C. Parkinson, Lara-Marie Barnes

University of Brighton

Research output: Contribution to conference › Abstract › peer-review

Abstract

Oral biofilms generally exist in a benign state in healthy individuals; however, a shift in the microbial community exacerbated by factors such as poor oral hygiene can result in dental disease. The aim of this study was to develop reproducible biofilms of the cariogenic bacteria Streptococcus sanguinis and Streptococcus mutans on surface-characterised poly(methyl methacrylate) (PMMA), bovine enamel and bovine dentine using a modified Robbins device (MRD) that allows control over key parameters including flow rate, shear force and temperature.

Original language	English
Publication status	Published - Sept 2009
Event	The British Pharmaceutical Conference 2009 - Manchester Duration: 1 Sept 2009 → …

Conference

Conference	The British Pharmaceutical Conference 2009
Period	1/09/09 → …

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title = "Development of an in-vitro model for oral biofilm studies",

abstract = "Oral biofilms generally exist in a benign state in healthy individuals; however, a shift in the microbial community exacerbated by factors such as poor oral hygiene can result in dental disease. The aim of this study was to develop reproducible biofilms of the cariogenic bacteria Streptococcus sanguinis and Streptococcus mutans on surface-characterised poly(methyl methacrylate) (PMMA), bovine enamel and bovine dentine using a modified Robbins device (MRD) that allows control over key parameters including flow rate, shear force and temperature.",

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T1 - Development of an in-vitro model for oral biofilm studies

AU - Adenuga, O.

AU - Charman, K.

AU - Churchley, D.

AU - Rees, G.

AU - Parkinson, C.

AU - Barnes, Lara-Marie

PY - 2009/9

Y1 - 2009/9

N2 - Oral biofilms generally exist in a benign state in healthy individuals; however, a shift in the microbial community exacerbated by factors such as poor oral hygiene can result in dental disease. The aim of this study was to develop reproducible biofilms of the cariogenic bacteria Streptococcus sanguinis and Streptococcus mutans on surface-characterised poly(methyl methacrylate) (PMMA), bovine enamel and bovine dentine using a modified Robbins device (MRD) that allows control over key parameters including flow rate, shear force and temperature.

AB - Oral biofilms generally exist in a benign state in healthy individuals; however, a shift in the microbial community exacerbated by factors such as poor oral hygiene can result in dental disease. The aim of this study was to develop reproducible biofilms of the cariogenic bacteria Streptococcus sanguinis and Streptococcus mutans on surface-characterised poly(methyl methacrylate) (PMMA), bovine enamel and bovine dentine using a modified Robbins device (MRD) that allows control over key parameters including flow rate, shear force and temperature.

M3 - Abstract

T2 - The British Pharmaceutical Conference 2009

Y2 - 1 September 2009

ER -

Development of an in-vitro model for oral biofilm studies

Abstract

Conference

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