Development of an in-vitro model for oral biofilm studies

O. Adenuga, K. Charman, D. Churchley, G. Rees, C. Parkinson, Lara-Marie Barnes

Research output: Contribution to conferenceAbstract

Abstract

Oral biofilms generally exist in a benign state in healthy individuals; however, a shift in the microbial community exacerbated by factors such as poor oral hygiene can result in dental disease. The aim of this study was to develop reproducible biofilms of the cariogenic bacteria Streptococcus sanguinis and Streptococcus mutans on surface-characterised poly(methyl methacrylate) (PMMA), bovine enamel and bovine dentine using a modified Robbins device (MRD) that allows control over key parameters including flow rate, shear force and temperature.
Original languageEnglish
Publication statusPublished - Sep 2009
EventThe British Pharmaceutical Conference 2009 - Manchester
Duration: 1 Sep 2009 → …

Conference

ConferenceThe British Pharmaceutical Conference 2009
Period1/09/09 → …

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Biofilms
Stomatognathic Diseases
Streptococcus mutans
Methacrylates
Oral Hygiene
Polymethyl Methacrylate
Dentin
Bacteria
Equipment and Supplies
Temperature
In Vitro Techniques

Cite this

Adenuga, O., Charman, K., Churchley, D., Rees, G., Parkinson, C., & Barnes, L-M. (2009). Development of an in-vitro model for oral biofilm studies. Abstract from The British Pharmaceutical Conference 2009, .
Adenuga, O. ; Charman, K. ; Churchley, D. ; Rees, G. ; Parkinson, C. ; Barnes, Lara-Marie. / Development of an in-vitro model for oral biofilm studies. Abstract from The British Pharmaceutical Conference 2009, .
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abstract = "Oral biofilms generally exist in a benign state in healthy individuals; however, a shift in the microbial community exacerbated by factors such as poor oral hygiene can result in dental disease. The aim of this study was to develop reproducible biofilms of the cariogenic bacteria Streptococcus sanguinis and Streptococcus mutans on surface-characterised poly(methyl methacrylate) (PMMA), bovine enamel and bovine dentine using a modified Robbins device (MRD) that allows control over key parameters including flow rate, shear force and temperature.",
author = "O. Adenuga and K. Charman and D. Churchley and G. Rees and C. Parkinson and Lara-Marie Barnes",
year = "2009",
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note = "The British Pharmaceutical Conference 2009 ; Conference date: 01-09-2009",

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Adenuga, O, Charman, K, Churchley, D, Rees, G, Parkinson, C & Barnes, L-M 2009, 'Development of an in-vitro model for oral biofilm studies' The British Pharmaceutical Conference 2009, 1/09/09, .

Development of an in-vitro model for oral biofilm studies. / Adenuga, O.; Charman, K.; Churchley, D.; Rees, G.; Parkinson, C.; Barnes, Lara-Marie.

2009. Abstract from The British Pharmaceutical Conference 2009, .

Research output: Contribution to conferenceAbstract

TY - CONF

T1 - Development of an in-vitro model for oral biofilm studies

AU - Adenuga, O.

AU - Charman, K.

AU - Churchley, D.

AU - Rees, G.

AU - Parkinson, C.

AU - Barnes, Lara-Marie

PY - 2009/9

Y1 - 2009/9

N2 - Oral biofilms generally exist in a benign state in healthy individuals; however, a shift in the microbial community exacerbated by factors such as poor oral hygiene can result in dental disease. The aim of this study was to develop reproducible biofilms of the cariogenic bacteria Streptococcus sanguinis and Streptococcus mutans on surface-characterised poly(methyl methacrylate) (PMMA), bovine enamel and bovine dentine using a modified Robbins device (MRD) that allows control over key parameters including flow rate, shear force and temperature.

AB - Oral biofilms generally exist in a benign state in healthy individuals; however, a shift in the microbial community exacerbated by factors such as poor oral hygiene can result in dental disease. The aim of this study was to develop reproducible biofilms of the cariogenic bacteria Streptococcus sanguinis and Streptococcus mutans on surface-characterised poly(methyl methacrylate) (PMMA), bovine enamel and bovine dentine using a modified Robbins device (MRD) that allows control over key parameters including flow rate, shear force and temperature.

M3 - Abstract

ER -

Adenuga O, Charman K, Churchley D, Rees G, Parkinson C, Barnes L-M. Development of an in-vitro model for oral biofilm studies. 2009. Abstract from The British Pharmaceutical Conference 2009, .