Cow's milk allergy: Therapeutic options and immunological aspects

T. Dean

    Research output: Contribution to journalArticlepeer-review


    Adverse reaction to cow's milk and infant formulas are common during infancy. Cow's milk has more than 20 constituent proteins and in principle many are capable of giving rise to an IgE mediated response. The prevalence of cow's milk allergy is between 0.5-10% of the paediatric population. The clinical diagnosis of cow's milk allergy is difficult because of the great diversity and varying severity of symptoms and is often based on criteria which is then confirmed by challenge with cow's milk. There is no doubt that various immunological mechanisms are involved in cow's milk allergy and in recent years a number of researchers have investigated the role of humoral and cell-mediated immunity in the pathogenesis of cow's milk allergy.

    Original languageEnglish
    JournalEuropean Journal of Clinical Nutrition
    Issue numberSUPPL. 1
    Publication statusPublished - 16 Oct 1995


    • Cow's milk allergy
    • IgE
    • IgG
    • T-lymphocytes


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