CAERvest® - a novel endothermic hypothermic device for core temperature cooling: safety and efficacy testing

Ashley Willmott, Alex Bliss, William H. Simpson, Steve M. Tocker, Rowland Cottingham, Neil Maxwell

Research output: Contribution to journalArticlepeer-review


Cooling of the body is used to treat hyperthermic individuals with heatstroke or to depress core temperature below normal for neuroprotection. A novel, chemically activated, unpowered cooling device, CAERvest®, was investigated for safety and efficacy. Methods. Eight healthy male participants (body mass 79.9±1.9 kg and body fat percentage 16.1±3.8%) visited the laboratory (20 °C, 40% relative humidity) on four occasions. Following 30-min rest, physiological and perceptual measures were recorded. Participants were then fitted with the CAERvest® proof of concept (PoC) or prototype 1 (P1), 2 (P2) or 3 (P3) for 60 min. Temperature, cardiovascular and perceptual measures were recorded every 5 min. After cooling, the CAERvest® was removed and the torso checked for cold-related injuries. Results. Temperature measures significantly (p <0.05) reduced pre to post in all trials. Larger reductions in core and skin temperatures were observed for PoC (-0.36±0.18 and -1.55±0.97 °C) and P3 (-0.36±0.22 and -2.47±0.82 °C), compared with P1 and P2. No signs of cold-related injury were observed at any stage. Conclusion. This study demonstrates that the CAERvest® is an effective device for reducing body temperature in healthy normothermic
Original languageEnglish
Pages (from-to)118-128
Number of pages11
JournalInternational Journal of Occupational Safety and Ergonomics
Issue number1
Publication statusPublished - 2 Feb 2017

Bibliographical note

This is an Accepted Manuscript of an article published by Taylor & Francis in International Journal of Occupational Safety and Ergonomics on 02/02/2017, available online:


  • thermoregulation
  • hyperthermia
  • heat-related illness
  • cooling
  • targeted temperature management


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