Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket

Keyphrases

• Anticonvulsant 100%
• KCNQ2 100%
• Channel Binding 100%
• KCNQ Potassium Channels 100%
• Binding Pocket 100%
• Mallotoxin 75%
• Valeric Acid 75%
• Molecular Mechanism 25%
• Modern Medicine 25%
• Two-component 25%
• Epilepsy 25%
• In Silico Docking 25%
• Seizure 25%
• Pentylenetetrazole 25%
• Voltage-gated Potassium Channel 25%
• Leaf Extract 25%
• 3-channel 25%
• Mallotus Oppositifolius 25%
• Heteromer 25%
• M-current 25%
• Ancient Medicine 25%
• Herbal Remedies 25%
• Mutagenesis 25%
• Tonic Seizures 25%
• Cellular Electrophysiology 25%
• Neuronal Excitability 25%
• Retigabine 25%

Medicine and Dentistry

• 3-Methylbutanoic Acid 100%
• Anticonvulsant 100%
• Potassium Channel KCNQ 100%
• Medicine 33%
• Excitability 33%
• In Silico 33%
• M Current 33%
• Pentylenetetrazol 33%
• Voltage-Gated Potassium Channel 33%
• Tonic Seizure 33%
• Retigabine 33%
• Mutagenesis 33%
• Epileptic Seizure 33%
• Heteromer 33%
• Electrophysiology 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Isovaleric Acid 100%
• Potassium Channel KCNQ 100%
• Anticonvulsive Agent 100%
• Pentetrazole 33%
• Mutagenesis 33%
• Voltage Gated Potassium Channel 33%
• Mallotus 33%
• Tonic Seizure 33%
• Retigabine 33%
• Herbal Remedy 33%
• Heteromer 33%