This study aimed to assess the effect of blood pressure and inflammation on the
cognitive symptoms of mild Alzheimer’s disease (AD) patients. Mid-life high blood
pressure is known to be a risk factor for dementia, whereas low blood pressure in older
age associates with poorer cognitive performance. Increased inflammation is also
associated with the development of AD, and so this study assessed the impact of both
blood pressure and inflammation on individual cognitive symptoms within AD patients.
The possible synergistic effect of blood pressure, markers of vascular health asymmetric
dimethylarginine (ADMA) and Fetuin-A, and markers of inflammation upon cognition
was also assessed.
|Date of Award||May 2016|