Embolic materials for the treatment of hypervasularised tumours are often non-degradable
hydrogels. In this thesis alginate hydrogel microspheres were synthesised and tested as a
potential biodegradable embolic agent. Degradation and compressibility were shown in vitro to
be dependent on the mannuronic acid to L-guluronic acid ratio, which was attributed to the
affinity of calcium to bind to the different alginate monomers. The microspheres were shown
to be deliverable and compatible with non-ionic radiopaque contrast media.
Date of Award | Jun 2009 |
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Original language | English |
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Awarding Institution | |
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Hydrogel microspheres for the treatment of tumours
Forster, R. E. J. (Author). Jun 2009
Student thesis: Doctoral Thesis