Cell cycle responses of glioma stem cells to ionizing radiation

  • Salih Yildirim

Student thesis: Doctoral Thesis


The Cancer Stem Cell (CSC) hypothesis has provided a novel theory of tumorigenesis by suggesting that mechanisms of organogenesis in developmental processes may be aberrantly active in neoplasms. This hypothesis proposes that CSCs within a tumour play the role of stem cells in a tissue. This novel approach not only leads to new insights into the origination of cancer, but also suggests that CSCs may be responsible for the resistance of several cancer types to current therapies. Thus, CSCs may also be targets for novel therapies.
Date of Award2011
Original languageEnglish
Awarding Institution
  • University of Brighton

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