AbstractThe Cancer Stem Cell (CSC) hypothesis has provided a novel theory of tumorigenesis by suggesting that mechanisms of organogenesis in developmental processes may be aberrantly active in neoplasms. This hypothesis proposes that CSCs within a tumour play the role of stem cells in a tissue. This novel approach not only leads to new insights into the origination of cancer, but also suggests that CSCs may be responsible for the resistance of several cancer types to current therapies. Thus, CSCs may also be targets for novel therapies.
|Date of Award||2011|
Cell cycle responses of glioma stem cells to ionizing radiation
Yildirim, S. (Author). 2011
Student thesis: Doctoral Thesis