A characterisation and functional analysis of the role of the 14-3-3-like proteins in neuronal ageing in the pond snail, Lymnaea stagnalis

Abstract

14-3-3 proteins are a ubiquitous family known for their ability to regulate myriad cellular processes including lifespan, neuronal signalling and transduction, protein trafficking and transmitter production and release. Previous work has shown that 14-3-3 proteins are linked to a variety of pathological neurodegenerative diseases although their role in healthy brain ageing is currently unclear.

Date of Award	Jul 2012
Original language	English
Awarding Institution	University of Brighton
Supervisor	Mark Yeoman (Supervisor), Katrin Jennert-Burston (Supervisor) & Jimi Adu (Supervisor)