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Water-mediated network in the resistance mechanism of fosfomycin
James McClory
, Jun Tang Lin
, David J. Timson
, Jian Zhang
, Meilan Huang
University of Brighton
Research output
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Keyphrases
Active Reaction
20%
Active Structure
20%
Antibiotic Therapy
20%
Associative Mechanism
20%
Catalytic Mechanism
20%
Chemical Reaction Mechanism
20%
Clinical Setting
20%
Developing Strategy
20%
Dissociative Disorders
20%
Effective Antibiotics
20%
Family Play
20%
FomA
80%
Fosfomycin
100%
Fosfomycin Resistance
20%
Molecular Dynamics Simulation
40%
Molecular Mechanics Calculations
20%
Phosphate Group
20%
Phosphate Transfer
40%
Phosphorylation
20%
Phosphorylation Reaction
20%
QM-MM
20%
Quantum Mechanics-molecular Mechanics
20%
Reaction Mechanism
20%
Resistance Mechanisms
100%
Transition State
20%
Urinary Tract Infection
20%
Valuable Insight
20%
Water Network
20%
Water-mediated
100%
WB97XD
20%
Biochemistry, Genetics and Molecular Biology
Adenosine Triphosphate
100%
Catalytic Mechanism
100%
Kinase A
100%
Molecular Mechanic
100%
Quantum Theory
100%