The metastability of human UDP-galactose 4 '-epimerase (GALE) is increased by variants associated with type III galactosemia but decreased by substrate and cofactor binding

Angel L. Pey, Esperanza Padin-Gonzalez, David Timson, Noel Mesa-Torres

Research output: Contribution to journalArticle

Original languageEnglish
Pages (from-to)103-114
Number of pages12
JournalArchives of Biochemistry and Biophysics
Volume562
Publication statusPublished - 15 Nov 2014

Keywords

  • Protein conformational stability
  • Protein dynamics
  • Protein aggregation
  • Proteolysis
  • Type III galactosemia
  • Ligand binding

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