The Management of Childhood Intracranial Tumours and the Role of the Ophthalmologist

Guy Mole, R. Edminson, A. Higham, Caroline Hopper, D. Hildebrand

Research output: Contribution to journalArticle

Abstract

Objective: This study looked at a single paediatric neuro-oncology centre’s experience of childhood intracranial tumours seen in the ophthalmology clinic over an approximately five-year period. This was used to analyse the role of the ophthalmologist in their long term follow up. Methods: A database was compiled of all children discussed at the neuro-oncology multi-disciplinary team (MDT) meeting between January 2012 and April 2017. All children who had an intracranial tumour determined by histology or suspected on neuro-imaging, who had also been seen in the ophthalmology clinic, were included. A retrospective case review was performed to create a record for each child. Results: The database contained 129 children of which 82 (64%) were boys and 47 (36%) were girls. Of these 89 (69%) had a histological diagnosis and 40 (31%) had a tumour suspected on neuroimaging. The most common tumour locations were the posterior fossa (n = 54, 42%), diencephalon (n = 20, 16%) and the visual pathways (n = 17, 13%). Papilloedema at first presentation was only found in 39 (30%) children. The most common other neuro-ophthalmic manifestations were non-paralytic strabismus (n=33), sixth nerve palsy (n=19) and seventh nerve palsy (n=12). Non-paralytic strabismus was a presenting symptom in only one case. There were 13 ophthalmic surgical procedures required for these children, the most common being strabismus surgery. Conclusion: We report the types and locations of paediatric intracranial tumours seen in the ophthalmology clinic as well as their neuro-ophthalmic manifestations. Only 30% presented with papilloedema and approximately 10% required an ophthalmic surgical procedure.

Original languageEnglish
Pages (from-to)375-381
Number of pages7
JournalNeuro-Ophthalmology
Volume43
Issue number6
DOIs
Publication statusPublished - 3 May 2019

Bibliographical note

This is an Accepted Manuscript of an article published by Taylor & Francis in Neuro-Ophthalmology on 3/5/2019, available online: http://www.tandfonline.com/10.1080/01658107.2019.1597130

Keywords

  • Brain tumour
  • neuro-ophthalmology
  • ophthalmic surgery

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