The cytotoxic assessment of carbon adsorbents

L. M. Barnes, M. C. Murphy, M. Melillo, G. J. Phillips, J. G. Davies, A. W. Lloyd, S. V. Mikhalovsky

Research output: Chapter in Book/Conference proceeding with ISSN or ISBNConference contribution with ISSN or ISBNpeer-review


A colony formation assay was used to assess the cytotoxic potential of a medical grade activated carbon adsorbent. It was observed that during extraction the adsorbent removed foetal calf serum (FCS) and other nutrients from the cell growth medium, making them unavailable to the cells during colony growth stage. The carbon adsorbent investigated was also found to be suitable for use in an extracorporeal device, for treatment of sepsis or acute renal failure. The results show that when carrying out cytotoxicity testing on highly porous adsorbent material, such as activated carbon, the methodology must be adapted to take into account the unusual material properties.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


ConferenceTransactions - 7th World Biomaterials Congress


Dive into the research topics of 'The cytotoxic assessment of carbon adsorbents'. Together they form a unique fingerprint.

Cite this