Synthesis and properties of (6,7-dimethoxy-4-coumaryl)alanine: A fluorescent peptide label

Fiona Bennett; David J. Barlow; Alexander N.O. Dodoo; Robert C. Hider; Alison Lansley; Jayne M. Lawrence; Christopher Marriott

doi:10.1006/abio.1999.4081

Synthesis and properties of (6,7-dimethoxy-4-coumaryl)alanine: A fluorescent peptide label

Fiona Bennett
, David J. Barlow
, Alexander N.O. Dodoo
, Robert C. Hider
, Alison Lansley
, Jayne M. Lawrence
, Christopher Marriott

University of Brighton

Research output: Contribution to journal › Article › peer-review

Abstract

The synthesis of racemic andl-(6,7-dimethoxy-4-coumaryl)alanine (Dmca) is described and some spectral and physicochemical properties are reported. The utility of Dmca as a highly sensitive and specific label for the quantitative detection of synthetic peptides in HPLC and in minimal essential media (MEM) is also described.

Original language	English
Pages (from-to)	15-23
Number of pages	9
Journal	Analytical Biochemistry
Volume	270
Issue number	1
DOIs	https://doi.org/10.1006/abio.1999.4081
Publication status	Published - 15 May 1999

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title = "Synthesis and properties of (6,7-dimethoxy-4-coumaryl)alanine: A fluorescent peptide label",

abstract = "The synthesis of racemic andl-(6,7-dimethoxy-4-coumaryl)alanine (Dmca) is described and some spectral and physicochemical properties are reported. The utility of Dmca as a highly sensitive and specific label for the quantitative detection of synthetic peptides in HPLC and in minimal essential media (MEM) is also described.",

author = "Fiona Bennett and Barlow, \{David J.\} and Dodoo, \{Alexander N.O.\} and Hider, \{Robert C.\} and Alison Lansley and Lawrence, \{Jayne M.\} and Christopher Marriott",

year = "1999",

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T1 - Synthesis and properties of (6,7-dimethoxy-4-coumaryl)alanine: A fluorescent peptide label

AU - Bennett, Fiona

AU - Barlow, David J.

AU - Dodoo, Alexander N.O.

AU - Hider, Robert C.

AU - Lansley, Alison

AU - Lawrence, Jayne M.

AU - Marriott, Christopher

PY - 1999/5/15

Y1 - 1999/5/15

N2 - The synthesis of racemic andl-(6,7-dimethoxy-4-coumaryl)alanine (Dmca) is described and some spectral and physicochemical properties are reported. The utility of Dmca as a highly sensitive and specific label for the quantitative detection of synthetic peptides in HPLC and in minimal essential media (MEM) is also described.

AB - The synthesis of racemic andl-(6,7-dimethoxy-4-coumaryl)alanine (Dmca) is described and some spectral and physicochemical properties are reported. The utility of Dmca as a highly sensitive and specific label for the quantitative detection of synthetic peptides in HPLC and in minimal essential media (MEM) is also described.

U2 - 10.1006/abio.1999.4081

DO - 10.1006/abio.1999.4081

M3 - Article

SN - 0003-2697

VL - 270

SP - 15

EP - 23

JO - Analytical Biochemistry

JF - Analytical Biochemistry

IS - 1

ER -

Synthesis and properties of (6,7-dimethoxy-4-coumaryl)alanine: A fluorescent peptide label

Abstract

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