Radiosensitivity of human T-lymphocytes proliferating in long term culture

S.Elizabeth James; C.F. Arlett; M.H.L. Green; B.A. Bridges

doi:10.1080/09553008314551391

Radiosensitivity of human T-lymphocytes proliferating in long term culture

S.Elizabeth James, C.F. Arlett, M.H.L. Green, B.A. Bridges

University of Brighton

Research output: Contribution to journal › Article › peer-review

Abstract

A method is described for determining the radiation sensitivity of dividing human T-lymphocytes in long-term culture. The results are fitted to a single-hit multi-target model. For cobalt-60 gamma radiationD0values of cells from five normal individuals range from 0·99 to 1·37 Gy with an overallD0of 1·09 Gy, and the extrapolation numbers range from 1·20 to 1·71 with an overall extrapolation number of 1·42.

Original language	English
Pages (from-to)	417-422
Number of pages	6
Journal	International Journal of Radiation Biology
Volume	44
Issue number	5
DOIs	https://doi.org/10.1080/09553008314551391
Publication status	Published - 31 Dec 1983

Keywords

human T-lymphocytes
radiosensitivity

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title = "Radiosensitivity of human T-lymphocytes proliferating in long term culture",

abstract = "A method is described for determining the radiation sensitivity of dividing human T-lymphocytes in long-term culture. The results are fitted to a single-hit multi-target model. For cobalt-60 gamma radiationD0values of cells from five normal individuals range from 0·99 to 1·37 Gy with an overallD0of 1·09 Gy, and the extrapolation numbers range from 1·20 to 1·71 with an overall extrapolation number of 1·42.",

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N2 - A method is described for determining the radiation sensitivity of dividing human T-lymphocytes in long-term culture. The results are fitted to a single-hit multi-target model. For cobalt-60 gamma radiationD0values of cells from five normal individuals range from 0·99 to 1·37 Gy with an overallD0of 1·09 Gy, and the extrapolation numbers range from 1·20 to 1·71 with an overall extrapolation number of 1·42.

AB - A method is described for determining the radiation sensitivity of dividing human T-lymphocytes in long-term culture. The results are fitted to a single-hit multi-target model. For cobalt-60 gamma radiationD0values of cells from five normal individuals range from 0·99 to 1·37 Gy with an overallD0of 1·09 Gy, and the extrapolation numbers range from 1·20 to 1·71 with an overall extrapolation number of 1·42.

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DO - 10.1080/09553008314551391

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JF - International Journal of Radiation Biology

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Radiosensitivity of human T-lymphocytes proliferating in long term culture

Abstract

Keywords

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