Prevalence of peanut allergy: a systematic review

Heather MacKenzie, C. Venter, Sally Kilburn, Harriet Moonesinghe, Kellyn Lee, Taraneh Dean

Research output: Contribution to conferenceAbstract

Abstract

Rationale: Describing geographical variations in the prevalence of peanut allergy helps inform evidence-based policy and practice. Methods: A systematic review methodology was employed. Studies were identified by searching Web of Science and PubMed, and by consultation with experts and screened for eligibility according to pre-specified criteria.Results: Prevalence data for peanut allergy was presented by 62 included studies; 28 presented data from one or more European countries and 26 from one or more non-European countries. Self-reported peanut allergy ranged from 0.0% (95% CI: 0.0-1.5%) to 15.0% (95% CI: 13.0-17.3%) in European countries, and from 0.0% (95% CI: 0.1-0.2%) to 8.4% (95% CI: 6.2%-11.2%) in non-European countries. Sensitisation ranged from 0.0% (95% CI: 0.0-12.0%) to 12.2% (95% CI: 9.7-15.2%) in European countries, and in non-European countries from 0.3% (95% CI: 0.0-2.1%) to 13.5% (95% CI: 11.6-15.7%).Reported prevalence in European countries ranged between 0.0% (95% CI: 0.0-4.2%) and 1.4% (95% CI: 0.9-2.3%) using open food challenges and a good clinical history, and between 0.0% (95% CI: 0.0-0.2%) and 2.8% (95% CI: 1.8-3.8%) using DBPCFC and a good clinical history. The single non-European study to utilise food challenges reported a prevalence of 2.9% (95% CI: 2.2-3.5%) based on open food challenges.Conclusions: Using the gold standard diagnostic method peanut allergy prevalence ranged between 0.0% (95% CI: 0.0-0.2%) and 2.8% (95% CI: 1.8-3.8%). Studies assessing the prevalence of peanut allergy varied widely in the age groups assessed and methods of diagnosis utilised. Challenge-proven data is sparse for non-European countries.
Original languageEnglish
Pages0-0
Number of pages1
Publication statusPublished - 23 Jan 2014
Event2014 AAAAI Annual Meeting - San Diego, CA, February 28 - March 4, 2014
Duration: 23 Jan 2014 → …

Conference

Conference2014 AAAAI Annual Meeting
Period23/01/14 → …

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