Preface: genomics and biology of exercise is undergoing a paradigm shift

Nir Eynon, Sarah Voisin, Alejandro Lucia, Guan Wang, Yannis Pitsiladis

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Genomics and Biology of Exercise is a field of research aiming at understanding how genetic variations influence adaptations to exercise training in healthy and diseased populations, elite athletes, and predisposition to exercise-related injuries. While the pioneering HERITAGE family study (HEalth, RIsk factors, exercise Training And GEnetics) acknowledged the importance of large, collaborative enterprises to obtain reliable results [1], many of the studies in the field have suffered from methodological errors, resulting in invalidated and non-replicated results [2]. Consequently, after more than 20 years of research in the field there remains no set of genetic variants available to predict exercise performance and predisposition to injuries in individuals [3]. However, the field of Genomics and Biology of Exercise is undergoing an urgently needed paradigm shift as an ever increasing number of scientists realise that working together is the best way to significantly advance the field.
Original languageEnglish
JournalBMC Genomics
Issue numberS8
Publication statusPublished - 14 Nov 2017

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