Preface: genomics and biology of exercise is undergoing a paradigm shift

Nir Eynon, Sarah Voisin, Alejandro Lucia, Guan Wang, Yannis Pitsiladis

Research output: Contribution to journalArticlepeer-review

Abstract

Genomics and Biology of Exercise is a field of research aiming at understanding how genetic variations influence adaptations to exercise training in healthy and diseased populations, elite athletes, and predisposition to exercise-related injuries. While the pioneering HERITAGE family study (HEalth, RIsk factors, exercise Training And GEnetics) acknowledged the importance of large, collaborative enterprises to obtain reliable results [1], many of the studies in the field have suffered from methodological errors, resulting in invalidated and non-replicated results [2]. Consequently, after more than 20 years of research in the field there remains no set of genetic variants available to predict exercise performance and predisposition to injuries in individuals [3]. However, the field of Genomics and Biology of Exercise is undergoing an urgently needed paradigm shift as an ever increasing number of scientists realise that working together is the best way to significantly advance the field.
Original languageEnglish
JournalBMC Genomics
Volume18
Issue numberS8
DOIs
Publication statusPublished - 14 Nov 2017

Bibliographical note

© The Author(s). 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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