Polysubstituted pyridazinones from sequential nucleophilic substitution reactions of tetrafluoropyridazine

Keyphrases

• Polysubstituted 100%
• Pyridazinone 100%
• Nucleophilic Substitution 100%
• Nucleophile 66%
• Aminated 66%
• Disubstituted 66%
• Ring-fused 66%
• Drug Discovery 33%
• Regioselectivity 33%
• Subsequent Reactions 33%
• Polyfunctional 33%
• Substitution Process 33%
• Nucleophilic Aromatic Substitution 33%
• Primary Amines 33%
• N-butylamine 33%
• Morpholine Derivatives 33%
• Aniline Derivatives 33%
• Secondary Amines 33%
• N,N,N′,N′-tetramethylethylenediamine 33%
• Nitrogen nucleophiles 33%

Chemistry

• Nucleophile 100%
• Pyridazinone 100%
• Nucleophilic Substitution 100%
• Drug Discovery 33%
• Fluorine 33%
• Nucleophilic Aromatic Substitution 33%
• Morpholine 33%
• Primary Amine 33%
• Regioselectivity 33%
• Secondary Amine 33%