Perfluorinated Heteroaromatic Systems as Scaffolds for Drug Discovery

David Armstrong; Matthew W. Cartwright; Emma L. Parks; Graham Pattison; Graham Sandford; Rachel Slater; Ian Wilson; John A. Christopher; David D. Miller; Paul W. Smith; Antonio Vong

doi:10.1002/9781444312096.ch11

Perfluorinated Heteroaromatic Systems as Scaffolds for Drug Discovery

David Armstrong
, Matthew W. Cartwright
, Emma L. Parks
, Graham Pattison
, Graham Sandford
, Rachel Slater
, Ian Wilson
, John A. Christopher
, David D. Miller
, Paul W. Smith
, Antonio Vong

Research output: Chapter in Book/Conference proceeding with ISSN or ISBN › Chapter › peer-review

Original language	English
Title of host publication	Fluorine in Medicinal Chemistry and Chemical Biology
Publisher	John Wiley & Sons, Ltd
Pages	291-311
Number of pages	21
ISBN (Print)	9781405167208
DOIs	https://doi.org/10.1002/9781444312096.ch11
Publication status	Published - 21 Apr 2009

Keywords

Advances in technology and high-throughput screening (HTS)
Biologically active heteroaromatic systems
Lipinski parameters (RO5) for predicting "drug-likeness" of potential molecular targets
Perfluorinated heteroaromatic systems as scaffolds for drug discovery
Perfluorinated heterocycles as core scaffolds
Privileged structures, core scaffolds and RAS in drug discovery process
Synthesis of 2-pyridone systems from pentafluoropyridine
Tetrafluoropyrimidine as a core scaffold

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10.1002/9781444312096.ch11

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Armstrong, D., Cartwright, M. W., Parks, E. L., Pattison, G., Sandford, G., Slater, R., Wilson, I., Christopher, J. A., Miller, D. D., Smith, P. W., & Vong, A. (2009). Perfluorinated Heteroaromatic Systems as Scaffolds for Drug Discovery. In Fluorine in Medicinal Chemistry and Chemical Biology (pp. 291-311). John Wiley & Sons, Ltd. https://doi.org/10.1002/9781444312096.ch11

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keywords = "Advances in technology and high-throughput screening (HTS), Biologically active heteroaromatic systems, Lipinski parameters (RO5) for predicting {"}drug-likeness{"} of potential molecular targets, Perfluorinated heteroaromatic systems as scaffolds for drug discovery, Perfluorinated heterocycles as core scaffolds, Privileged structures, core scaffolds and RAS in drug discovery process, Synthesis of 2-pyridone systems from pentafluoropyridine, Tetrafluoropyrimidine as a core scaffold",

author = "David Armstrong and Cartwright, \{Matthew W.\} and Parks, \{Emma L.\} and Graham Pattison and Graham Sandford and Rachel Slater and Ian Wilson and Christopher, \{John A.\} and Miller, \{David D.\} and Smith, \{Paul W.\} and Antonio Vong",

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doi = "10.1002/9781444312096.ch11",

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T1 - Perfluorinated Heteroaromatic Systems as Scaffolds for Drug Discovery

AU - Armstrong, David

AU - Cartwright, Matthew W.

AU - Parks, Emma L.

AU - Pattison, Graham

AU - Sandford, Graham

AU - Slater, Rachel

AU - Wilson, Ian

AU - Christopher, John A.

AU - Miller, David D.

AU - Smith, Paul W.

AU - Vong, Antonio

PY - 2009/4/21

Y1 - 2009/4/21

KW - Advances in technology and high-throughput screening (HTS)

KW - Biologically active heteroaromatic systems

KW - Lipinski parameters (RO5) for predicting "drug-likeness" of potential molecular targets

KW - Perfluorinated heteroaromatic systems as scaffolds for drug discovery

KW - Perfluorinated heterocycles as core scaffolds

KW - Privileged structures, core scaffolds and RAS in drug discovery process

KW - Synthesis of 2-pyridone systems from pentafluoropyridine

KW - Tetrafluoropyrimidine as a core scaffold

UR - https://www.scopus.com/pages/publications/84889333160

U2 - 10.1002/9781444312096.ch11

DO - 10.1002/9781444312096.ch11

M3 - Chapter

AN - SCOPUS:84889333160

SN - 9781405167208

SP - 291

EP - 311

BT - Fluorine in Medicinal Chemistry and Chemical Biology

PB - John Wiley & Sons, Ltd

ER -

Perfluorinated Heteroaromatic Systems as Scaffolds for Drug Discovery

Keywords

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