Malaria and helminthic co-infection during pregnancy causes fetomaternal haemorrhage and foetal growth retardation. This study determined the pooled burden of pregnancy malaria and helminthic co-infection in sub-Saharan Africa. CINAHL, EMBASE, Google Scholar, Scopus, PubMed, and Web of Science databases were used to retrieve data from the literature, without restricting language and publication year. The Joanna Briggs Institute's critical appraisal tool for prevalence studies was used for quality assessment. STATA Version 14.0 was used to conduct the meta-analysis. The I2 statistics and Egger's test were used to test heterogeneity and publication bias. The random-effects model was used to estimate the pooled prevalence at a 95% confidence interval (CI). The review protocol has been registered in PROSPERO, with the number CRD42019144812. In total, 24 studies (n = 14,087 participants) were identified in this study. The pooled analysis revealed that 20% of pregnant women were co-infected by malaria and helminths in sub-Saharan Africa. The pooled prevalence of malaria and helminths were 33% and 35%, respectively. The most prevalent helminths were Hookworm (48%), Ascaris lumbricoides (37%), and Trichuris trichiura (15%). Significantly higher malaria and helminthic co-infection during pregnancy were observed. Health systems in sub-Saharan Africa must implement home-grown innovative solutions to underpin context-specific policies for the early initiation of effective intermittent preventive therapy.
|Number of pages||22|
|Journal||International journal of environmental research and public health|
|Publication status||Published - 29 Apr 2022|
Bibliographical noteFunding Information:
The Armauer Hansen Research Institute for enabling us and granting access to the databases and The Joanna Briggs Institute (JBI), for helping us with access to the databases and development of the review protocol. The Evidence-Based Healthcare Centre at Jimma University in Ethiopia provided us with a comprehensive systematic review training opportunity.
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
- Sub-Saharan Africa
- Helminthic Infections
- Pregnancy Malaria
- Pregnant Women
- Africa South of the Sahara