Lipid monolayer spontaneous curvatures: a collection of published values

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Lipid monolayer spontaneous curvatures (or lipid intrinsic curvatures) are one of several material properties of lipids that enable the stored curvature elastic energy in a lipid aggregate to be determined. Stored curvature elastic energy is important since it can modulate the function of membrane proteins and plays a role in the regulatory pathways of phospholipid homeostasis. Due to the large number of different lipid molecules that might theoretically exist in nature, very few lipid spontaneous curvatures have been determined. Herein the values of lipid spontaneous curvatures that exist in the literature are collected, alongside key experimental details. Where possible, trends in the data are discussed and finally, obvious gaps in the knowledge are signposted.

Original languageEnglish
Article number105117
JournalChemistry and Physics of Lipids
Publication statusPublished - 12 Jul 2021


  • Elastic theory of membranes
  • Intrinsic curvature hypothesis
  • Lipid intrinsic curvature
  • Lipid monolayer spontaneous curvature
  • Membrane curvature


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