L-(6,7-dimethoxy-4-coumaryl) alanine: an intrinsic probe for the labelling of peptides

Fiona Bennett; David J. Barlow; Alexander N.O. Dodoo; Robert C. Hider; Alison Lansley; Jayne M. Lawrence; Christopher Marriott

doi:10.1016/S0040-4039(97)01753-X

L-(6,7-dimethoxy-4-coumaryl) alanine: an intrinsic probe for the labelling of peptides

Fiona Bennett, David J. Barlow, Alexander N.O. Dodoo, Robert C. Hider, Alison Lansley, Jayne M. Lawrence, Christopher Marriott

University of Brighton

Research output: Contribution to journal › Article › peer-review

Abstract

The asymmetric synthesis, spectral properties and incorporation into solid phase peptide synthesis are described for L-(6,7-dimethoxy-4-coumaryl)alanine (Dca). Dca has great utility as a specific and highly sensitive intrinsic probe for fluorescence labelling and quantitation of peptides and proteins.

Original language	English
Pages (from-to)	7449-7452
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	42
DOIs	https://doi.org/10.1016/S0040-4039(97)01753-X
Publication status	Published - 20 Oct 1997

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@article{6c81cb81e981431197d9f42a826cdb50,

title = "L-(6,7-dimethoxy-4-coumaryl) alanine: an intrinsic probe for the labelling of peptides",

abstract = "The asymmetric synthesis, spectral properties and incorporation into solid phase peptide synthesis are described for L-(6,7-dimethoxy-4-coumaryl)alanine (Dca). Dca has great utility as a specific and highly sensitive intrinsic probe for fluorescence labelling and quantitation of peptides and proteins.",

author = "Fiona Bennett and Barlow, \{David J.\} and Dodoo, \{Alexander N.O.\} and Hider, \{Robert C.\} and Alison Lansley and Lawrence, \{Jayne M.\} and Christopher Marriott",

year = "1997",

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day = "20",

doi = "10.1016/S0040-4039(97)01753-X",

language = "English",

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journal = "Tetrahedron Letters",

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TY - JOUR

T1 - L-(6,7-dimethoxy-4-coumaryl) alanine: an intrinsic probe for the labelling of peptides

AU - Bennett, Fiona

AU - Barlow, David J.

AU - Dodoo, Alexander N.O.

AU - Hider, Robert C.

AU - Lansley, Alison

AU - Lawrence, Jayne M.

AU - Marriott, Christopher

PY - 1997/10/20

Y1 - 1997/10/20

N2 - The asymmetric synthesis, spectral properties and incorporation into solid phase peptide synthesis are described for L-(6,7-dimethoxy-4-coumaryl)alanine (Dca). Dca has great utility as a specific and highly sensitive intrinsic probe for fluorescence labelling and quantitation of peptides and proteins.

AB - The asymmetric synthesis, spectral properties and incorporation into solid phase peptide synthesis are described for L-(6,7-dimethoxy-4-coumaryl)alanine (Dca). Dca has great utility as a specific and highly sensitive intrinsic probe for fluorescence labelling and quantitation of peptides and proteins.

U2 - 10.1016/S0040-4039(97)01753-X

DO - 10.1016/S0040-4039(97)01753-X

M3 - Article

SN - 0040-4039

VL - 38

SP - 7449

EP - 7452

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 42

ER -

L-(6,7-dimethoxy-4-coumaryl) alanine: an intrinsic probe for the labelling of peptides

Abstract

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