IR laser desorption of oligonucleotides: A novel gas phase target for radiation damage studies

T. L. Merrigan, C. A. Hunniford, D. J. Timson, M. Catney, R. W. McCullough

Research output: Contribution to journalArticlepeer-review

Abstract

The desorption of oligonucleotides by 3 μ m laser irradiation has been studied by laser induced fluorescence imaging of the resulting gas phase plumes. Fitting of the plume data has been achieved by using a modified Maxwell Boltzmann distribution which incorporates a range of stream velocities. Spatial density profiles, velocities and temperature variation have been determined from these fits indicating that the oligonucleotide plume only achieves a partial thermal relaxation. This laser desorption technique may provide a means of overcoming the limited mass range of gas phase biomolecules available from thermal evaporation techniques.

Original languageEnglish
Pages (from-to)163-169
Number of pages7
JournalEuropean Physical Journal D
Volume60
Issue number1
DOIs
Publication statusPublished - 1 Oct 2010

Fingerprint

Dive into the research topics of 'IR laser desorption of oligonucleotides: A novel gas phase target for radiation damage studies'. Together they form a unique fingerprint.

Cite this