FAD binding overcomes defects in activity and stability displayed by cancer-associated variants of human NQO1

Angel L. Pey, Clare F. Megarity, David Timson

Research output: Contribution to journalArticle

Original languageEnglish
Pages (from-to)2163-2173
Number of pages11
JournalBBA - Molecular Basis of Disease
Volume1842
Issue number11
DOIs
Publication statusPublished - 30 Nov 2014

Keywords

  • NAD(P)H quinone oxidoreductase 1
  • Cancer-associated polymorphism
  • NQO1*2
  • NQO1*3
  • Kinetic instability

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