Experimental design - Challenges in conducting electrochemical measurements for bioanalysis

This chapter provides a key transition within the book. In chapters 1-5 we have learnt about the main techniques and tools that have been utilized in electroanalytical measurements. However, the key variables that need to be considered in conducting bioanalytical measurements when utilizing electrochemistry have not yet been examined. This chapter will highlight the key variables that can influence the accuracy of measurements conducted in biological environments, and that thus needs to be considered prior to conducting measurements. The chapter will explore three different areas: the electrode and instrumentation; experimental conditions and biological variables. Each of these factors will be explained in detail with strategies that can be used to enhance the accuracy and robustness of measurements.