Evidence for ‘lock and key’ character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes

S. Sonkaria; G. Boucher; J. Florez-Alvarez; B. Said; S. Hussain; Elizabeth Ostler; S. Gul; E.W. Thomas; M. Resmini; Gerard Gallacher; K. Brocklehurst

doi:10.1042/BJ20031966

Evidence for ‘lock and key’ character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes

S. Sonkaria
, G. Boucher
, J. Florez-Alvarez
, B. Said
, S. Hussain
, Elizabeth Ostler
, S. Gul
, E.W. Thomas
, M. Resmini
, Gerard Gallacher
, K. Brocklehurst

University of Brighton

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	125-130
Number of pages	6
Journal	Biochemical Journal
Volume	381
Issue number	1
DOIs	https://doi.org/10.1042/BJ20031966
Publication status	Published - Jul 2004

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Cite this

Sonkaria, S., Boucher, G., Florez-Alvarez, J., Said, B., Hussain, S., Ostler, E., Gul, S., Thomas, E. W., Resmini, M., Gallacher, G., & Brocklehurst, K. (2004). Evidence for ‘lock and key’ character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes. Biochemical Journal, 381(1), 125-130. https://doi.org/10.1042/BJ20031966

Sonkaria, S. ; Boucher, G. ; Florez-Alvarez, J. et al. / Evidence for ‘lock and key’ character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes. In: Biochemical Journal. 2004 ; Vol. 381, No. 1. pp. 125-130.

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title = "Evidence for {\textquoteleft}lock and key{\textquoteright} character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes",

author = "S. Sonkaria and G. Boucher and J. Florez-Alvarez and B. Said and S. Hussain and Elizabeth Ostler and S. Gul and E.W. Thomas and M. Resmini and Gerard Gallacher and K. Brocklehurst",

year = "2004",

month = jul,

doi = "10.1042/BJ20031966",

language = "English",

volume = "381",

pages = "125--130",

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Sonkaria, S, Boucher, G, Florez-Alvarez, J, Said, B, Hussain, S, Ostler, E, Gul, S, Thomas, EW, Resmini, M, Gallacher, G & Brocklehurst, K 2004, 'Evidence for ‘lock and key’ character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes', Biochemical Journal, vol. 381, no. 1, pp. 125-130. https://doi.org/10.1042/BJ20031966

Evidence for ‘lock and key’ character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes. / Sonkaria, S.; Boucher, G.; Florez-Alvarez, J. et al.
In: Biochemical Journal, Vol. 381, No. 1, 07.2004, p. 125-130.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Evidence for ‘lock and key’ character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes

AU - Sonkaria, S.

AU - Boucher, G.

AU - Florez-Alvarez, J.

AU - Said, B.

AU - Hussain, S.

AU - Ostler, Elizabeth

AU - Gul, S.

AU - Thomas, E.W.

AU - Resmini, M.

AU - Gallacher, Gerard

AU - Brocklehurst, K.

PY - 2004/7

Y1 - 2004/7

U2 - 10.1042/BJ20031966

DO - 10.1042/BJ20031966

M3 - Article

SN - 1470-8728

VL - 381

SP - 125

EP - 130

JO - Biochemical Journal

JF - Biochemical Journal

IS - 1

ER -

Sonkaria S, Boucher G, Florez-Alvarez J, Said B, Hussain S, Ostler E et al. Evidence for ‘lock and key’ character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes. Biochemical Journal. 2004 Jul;381(1):125-130. doi: 10.1042/BJ20031966