Engineering of TIMP‐3 as a LAP‐fusion protein for targeting to sites of inflammation

Keyphrases

• Inflammation 100%
• TIMP3 100%
• Matrix Metalloproteinases 33%
• Adamalysin 33%
• Specific Inhibitor 16%
• Arthritis 16%
• Human Joints 16%
• Drug Delivery 16%
• Recombinant 16%
• Thrombospondin-1 (TSP-1) 16%
• Protease 16%
• Connective Tissue 16%
• Osteoarthritis 16%
• Mammalian Cells 16%
• Native Protein 16%
• Protease Activity 16%
• Synovial Fluid 16%
• Peptide Fusion 16%
• Catabolic Enzymes 16%
• Potential for Development 16%
• Natural Inhibitors 16%
• Therapeutic Proteins 16%
• Novel Therapies 16%

Biochemistry, Genetics and Molecular Biology

• TIMP3 100%
• Matrix Metalloproteinase 40%
• Adamalysin 40%
• Protease 40%
• Upregulation 20%
• Enzyme 20%
• Cytokine 20%
• Thrombospondin 20%
• Metalloprotease Inhibitor 20%

Immunology and Microbiology

• Thrombospondin 16%