Effects of low energy carbon ions on plasmid DNA

C. A. Hunniford; D. J. Timson; R. J.H. Davies; R. W. McCullough

doi:10.1088/1742-6596/101/1/012012

Effects of low energy carbon ions on plasmid DNA

C. A. Hunniford, D. J. Timson, R. J.H. Davies, R. W. McCullough

Research output: Contribution to journal › Article › peer-review

Abstract

The damage induced in supercoiled plasmid DNA molecules by low energy (< 1 keV u^-1) singly and doubly charged carbon ions has been investigated as a function of ion exposure. The production of short linear fragments through multiple double strand breakage is indicated and exponential exposure responses for each of the topoisomers are presented. The damage produced by C²⁺ is apparent at much lower ion exposures that with C⁺.

Original language	English
Article number	012012
Journal	Journal of Physics: Conference Series
Volume	101
Issue number	1
DOIs	https://doi.org/10.1088/1742-6596/101/1/012012
Publication status	Published - 1 Feb 2008

Access to Document

10.1088/1742-6596/101/1/012012

Cite this

@article{99a0a6902c5641148bc44ff7365b3400,

title = "Effects of low energy carbon ions on plasmid DNA",

abstract = "The damage induced in supercoiled plasmid DNA molecules by low energy (< 1 keV u-1) singly and doubly charged carbon ions has been investigated as a function of ion exposure. The production of short linear fragments through multiple double strand breakage is indicated and exponential exposure responses for each of the topoisomers are presented. The damage produced by C2+ is apparent at much lower ion exposures that with C+.",

author = "Hunniford, {C. A.} and Timson, {D. J.} and Davies, {R. J.H.} and McCullough, {R. W.}",

year = "2008",

month = feb,

day = "1",

doi = "10.1088/1742-6596/101/1/012012",

language = "English",

volume = "101",

journal = "Journal of Physics: Conference Series",

issn = "1742-6588",

number = "1",

}

TY - JOUR

T1 - Effects of low energy carbon ions on plasmid DNA

AU - Hunniford, C. A.

AU - Timson, D. J.

AU - Davies, R. J.H.

AU - McCullough, R. W.

PY - 2008/2/1

Y1 - 2008/2/1

N2 - The damage induced in supercoiled plasmid DNA molecules by low energy (< 1 keV u-1) singly and doubly charged carbon ions has been investigated as a function of ion exposure. The production of short linear fragments through multiple double strand breakage is indicated and exponential exposure responses for each of the topoisomers are presented. The damage produced by C2+ is apparent at much lower ion exposures that with C+.

AB - The damage induced in supercoiled plasmid DNA molecules by low energy (< 1 keV u-1) singly and doubly charged carbon ions has been investigated as a function of ion exposure. The production of short linear fragments through multiple double strand breakage is indicated and exponential exposure responses for each of the topoisomers are presented. The damage produced by C2+ is apparent at much lower ion exposures that with C+.

UR - http://www.scopus.com/inward/record.url?scp=44649094689&partnerID=8YFLogxK

U2 - 10.1088/1742-6596/101/1/012012

DO - 10.1088/1742-6596/101/1/012012

M3 - Article

AN - SCOPUS:44649094689

SN - 1742-6588

VL - 101

JO - Journal of Physics: Conference Series

JF - Journal of Physics: Conference Series

IS - 1

M1 - 012012

ER -

Effects of low energy carbon ions on plasmid DNA

Abstract

Access to Document

Other files and links

Fingerprint

Cite this