Effective microorganism – X attenuates circulating superoxide dismutase following an acute bout of intermittent running in hot, humid conditions

Lee Taylor, Ben J. Lee, Oliver Gibson, Adrian W. Midgley, Peter Watt, A.R. Mauger, Paul C. Castle

Research output: Contribution to journalArticle

Abstract

This study determined the effectiveness of antioxidant supplementa- tion on high-intensity exercise-heat stress. Six males completed a high- intensity running protocol twice in temperate conditions (TEMP; 20.4°C), and twice in hot conditions (HOT; 34.7°C). Trials were completed following 7 days supplementation with 70 ml·day −1 effective microorganism-X (EM-X; TEMPEMX or HOTEMX) or placebo (TEMPPLA or HOTPLA). Plasma extracellular Hsp72 (eHsp72) and superoxide dismutase (SOD) were measured by ELISA. eHsp72 and SOD increased pre-post exercise (p < 0.001), with greater eHsp72 (p < 0.001) increases observed in HOT (+1.5 ng·ml−1) compared to TEMP (+0.8 ng·ml−1). EM-X did not influence eHsp72 (p > 0.05). Greater (p < 0.001) SOD increases were observed in HOT (+0.22 U·ml−1) versus TEMP (+0.10 U·ml−1) with SOD reduced in HOTEMX versus HOTPLA (p = 0.001). Physiological and perceptual responses were all greater (p < 0.001) in HOT versus TEMP conditions, with no difference followed EM-X (p > 0.05). EM-X supplementation attenuated the SOD increases following HOT, potentiating its application as an ergogenic aid to ameliorate oxidative stress.
Original languageEnglish
Pages (from-to)130-144
Number of pages15
JournalResearch in Sports Medicine
Volume24
Issue number2
DOIs
Publication statusPublished - 31 Mar 2016

Bibliographical note

This is an Accepted Manuscript of an article published by Taylor & Francis in Research in Sports Medicine on 31/03/2016, available online: http://www.tandfonline.com/10.1080/15438627.2015.1126279

Keywords

  • heat shock proteins (HSP)
  • oxidative stress
  • redox balance
  • repeated sprint
  • exercise
  • HIT
  • human

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