Different measures of dietary diversity during infancy and the association with childhood food allergy in a UK birth cohort study

Carina Venter, Kate Maslin, John W. Holloway, Lori J. Silveira, David M. Fleischer, Tara Dean, Syed Hasan Arshad

Research output: Contribution to journalArticle

Abstract

Background: Diet Diversity (DD) during infancy may prevent food allergies (FA), possibly by exposing the gastrointestinal microbiota to diverse foods and nutrients.

Objective: To investigate the association between four different measures of DD during infancy and development of FA over the first decade of life.

Methods: A birth cohort born between 2001/2002 were followed prospectively, providing information on socio-demographic, environmental and dietary exposures. Information on age of introduction of a range of foods and food allergens were collected during infancy. Children were assessed for food allergy at 1, 2, 3 and 10 years. DD was defined using four measures in the first year of life: the World Health Organisation (WHO) definition of minimum DD at 6 months, as food diversity (FD) and fruit and vegetable diversity (FVD) at 3, 6 and 9 months, and as food allergen diversity (FAD) at 3, 6, 9, 12 months.

Results: 969 pregnant women were recruited at 12 weeks gestation. 900, 858, 891 and 827 offspring were assessed at 1, 2, 3 and 10 years. Univariate analysis showed that WHO DD (p=0.0047), FD (p=0.0009), FAD (p=0.0048) and FVD (p=0.0174) at 6 months and FD (p=0.0392), FAD (p=0.0233), and FVD (0.0163) at 9 months significantly reduced the odds of FA over the first decade of life. DD measures at 3 months were not associated with FA but only 33% of the cohort had solid foods introduced by this age.

Conclusion: Increased infant DD, as measured by four different methods, decreased the likelihood of developing FA.
Original languageEnglish
JournalThe Journal of Allergy and Clinical Immunology: In Practice
DOIs
Publication statusPublished - 28 Jan 2020

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Food Hypersensitivity
Cohort Studies
Parturition
Food
Diet
Allergens
Vegetables
Fruit
Environmental Exposure
Pregnant Women
Demography

Keywords

  • Dietary variety
  • dietary diversity
  • eczema
  • weaning
  • complementary feeding
  • infant feeding
  • food allergy prevention

Cite this

@article{65db798413c14ba3a27b56f7f795f036,
title = "Different measures of dietary diversity during infancy and the association with childhood food allergy in a UK birth cohort study",
abstract = "Background: Diet Diversity (DD) during infancy may prevent food allergies (FA), possibly by exposing the gastrointestinal microbiota to diverse foods and nutrients.Objective: To investigate the association between four different measures of DD during infancy and development of FA over the first decade of life.Methods: A birth cohort born between 2001/2002 were followed prospectively, providing information on socio-demographic, environmental and dietary exposures. Information on age of introduction of a range of foods and food allergens were collected during infancy. Children were assessed for food allergy at 1, 2, 3 and 10 years. DD was defined using four measures in the first year of life: the World Health Organisation (WHO) definition of minimum DD at 6 months, as food diversity (FD) and fruit and vegetable diversity (FVD) at 3, 6 and 9 months, and as food allergen diversity (FAD) at 3, 6, 9, 12 months.Results: 969 pregnant women were recruited at 12 weeks gestation. 900, 858, 891 and 827 offspring were assessed at 1, 2, 3 and 10 years. Univariate analysis showed that WHO DD (p=0.0047), FD (p=0.0009), FAD (p=0.0048) and FVD (p=0.0174) at 6 months and FD (p=0.0392), FAD (p=0.0233), and FVD (0.0163) at 9 months significantly reduced the odds of FA over the first decade of life. DD measures at 3 months were not associated with FA but only 33{\%} of the cohort had solid foods introduced by this age.Conclusion: Increased infant DD, as measured by four different methods, decreased the likelihood of developing FA.",
keywords = "Dietary variety, dietary diversity, eczema, weaning, complementary feeding, infant feeding, food allergy prevention",
author = "Carina Venter and Kate Maslin and Holloway, {John W.} and Silveira, {Lori J.} and Fleischer, {David M.} and Tara Dean and Arshad, {Syed Hasan}",
year = "2020",
month = "1",
day = "28",
doi = "10.1016/j.jaip.2020.01.029",
language = "English",
journal = "The Journal of Allergy and Clinical Immunology: In Practice",
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Different measures of dietary diversity during infancy and the association with childhood food allergy in a UK birth cohort study. / Venter, Carina; Maslin, Kate; Holloway, John W.; Silveira, Lori J.; Fleischer, David M. ; Dean, Tara; Arshad, Syed Hasan.

In: The Journal of Allergy and Clinical Immunology: In Practice, 28.01.2020.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Different measures of dietary diversity during infancy and the association with childhood food allergy in a UK birth cohort study

AU - Venter, Carina

AU - Maslin, Kate

AU - Holloway, John W.

AU - Silveira, Lori J.

AU - Fleischer, David M.

AU - Dean, Tara

AU - Arshad, Syed Hasan

PY - 2020/1/28

Y1 - 2020/1/28

N2 - Background: Diet Diversity (DD) during infancy may prevent food allergies (FA), possibly by exposing the gastrointestinal microbiota to diverse foods and nutrients.Objective: To investigate the association between four different measures of DD during infancy and development of FA over the first decade of life.Methods: A birth cohort born between 2001/2002 were followed prospectively, providing information on socio-demographic, environmental and dietary exposures. Information on age of introduction of a range of foods and food allergens were collected during infancy. Children were assessed for food allergy at 1, 2, 3 and 10 years. DD was defined using four measures in the first year of life: the World Health Organisation (WHO) definition of minimum DD at 6 months, as food diversity (FD) and fruit and vegetable diversity (FVD) at 3, 6 and 9 months, and as food allergen diversity (FAD) at 3, 6, 9, 12 months.Results: 969 pregnant women were recruited at 12 weeks gestation. 900, 858, 891 and 827 offspring were assessed at 1, 2, 3 and 10 years. Univariate analysis showed that WHO DD (p=0.0047), FD (p=0.0009), FAD (p=0.0048) and FVD (p=0.0174) at 6 months and FD (p=0.0392), FAD (p=0.0233), and FVD (0.0163) at 9 months significantly reduced the odds of FA over the first decade of life. DD measures at 3 months were not associated with FA but only 33% of the cohort had solid foods introduced by this age.Conclusion: Increased infant DD, as measured by four different methods, decreased the likelihood of developing FA.

AB - Background: Diet Diversity (DD) during infancy may prevent food allergies (FA), possibly by exposing the gastrointestinal microbiota to diverse foods and nutrients.Objective: To investigate the association between four different measures of DD during infancy and development of FA over the first decade of life.Methods: A birth cohort born between 2001/2002 were followed prospectively, providing information on socio-demographic, environmental and dietary exposures. Information on age of introduction of a range of foods and food allergens were collected during infancy. Children were assessed for food allergy at 1, 2, 3 and 10 years. DD was defined using four measures in the first year of life: the World Health Organisation (WHO) definition of minimum DD at 6 months, as food diversity (FD) and fruit and vegetable diversity (FVD) at 3, 6 and 9 months, and as food allergen diversity (FAD) at 3, 6, 9, 12 months.Results: 969 pregnant women were recruited at 12 weeks gestation. 900, 858, 891 and 827 offspring were assessed at 1, 2, 3 and 10 years. Univariate analysis showed that WHO DD (p=0.0047), FD (p=0.0009), FAD (p=0.0048) and FVD (p=0.0174) at 6 months and FD (p=0.0392), FAD (p=0.0233), and FVD (0.0163) at 9 months significantly reduced the odds of FA over the first decade of life. DD measures at 3 months were not associated with FA but only 33% of the cohort had solid foods introduced by this age.Conclusion: Increased infant DD, as measured by four different methods, decreased the likelihood of developing FA.

KW - Dietary variety

KW - dietary diversity

KW - eczema

KW - weaning

KW - complementary feeding

KW - infant feeding

KW - food allergy prevention

U2 - 10.1016/j.jaip.2020.01.029

DO - 10.1016/j.jaip.2020.01.029

M3 - Article

JO - The Journal of Allergy and Clinical Immunology: In Practice

JF - The Journal of Allergy and Clinical Immunology: In Practice

SN - 2213-2198

ER -