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Cyclin D1 over-expression permits the reproducible detection of senescent human vascular smooth muscle cells
D. Burton
,
Angela Sheerin
, Elizabeth Ostler
, K. Smith
, P.J. Giles
, J. Lowe
, W. Rhys-Williams
, D.G. Kipling
,
Richard Faragher
University of Brighton
Research output
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Keyphrases
Overexpression
100%
Human Vascular Smooth muscle Cells
100%
Cyclin D1 (CCND1)
100%
Senescence
40%
Late Passage
20%
Passage Culture
20%
Replicative Senescence
20%
Comets
20%
Senescent Cells
20%
Organismal Aging
20%
Potential Barrier
20%
Transcriptome Comparison
20%
Mitotic Cells
20%
Cytochemical
20%
TUNEL Staining
20%
Vascular Smooth muscle Cells
20%
Normal Cell Line
20%
New Markers
20%
Senescence-associated
20%
β-Galactosidase (β-Gal)
20%
Ki67 Staining
20%
Resveratrol
20%
Cell Growth
20%
Cell Turnover
20%
Protein Level
20%
Anti-aging
20%
Competent Cells
20%
Causal Role
20%
Growth Kinetics
20%
Neuroscience
Cyclin D1
100%
Vascular Smooth Muscle
100%
In Vitro
16%
Cell Growth
16%
TUNEL Assay
16%
Transcriptomics
16%
Resveratrol
16%
Galactosidase
16%
Biochemistry, Genetics and Molecular Biology
Galactosidase
33%
Medicine and Dentistry
Galactosidase
16%