Conformational changes to plasmid DNA induced by low energy carbon ions

C. A. Hunniford; D. J. Timson; R. J.H. Davies; R. W. McCullough

doi:10.1088/1742-6596/58/1/080

Conformational changes to plasmid DNA induced by low energy carbon ions

C. A. Hunniford, D. J. Timson, R. J.H. Davies, R. W. McCullough

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Abstract

The damage induced in supercoiled plasmid DNA molecules by low energy (<500 eVu^-1) carbon ions has been investigated as a function of ion dose. The production of short linear fragments through multiple double strand breakage is suggested and exponential dose responses for each of the topoisomers are presented.

Original language	English
Article number	080
Pages (from-to)	355-358
Number of pages	4
Journal	Journal of Physics: Conference Series
Volume	58
Issue number	1
DOIs	https://doi.org/10.1088/1742-6596/58/1/080
Publication status	Published - 1 Mar 2007

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title = "Conformational changes to plasmid DNA induced by low energy carbon ions",

abstract = "The damage induced in supercoiled plasmid DNA molecules by low energy (<500 eVu-1) carbon ions has been investigated as a function of ion dose. The production of short linear fragments through multiple double strand breakage is suggested and exponential dose responses for each of the topoisomers are presented.",

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AU - Davies, R. J.H.

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AB - The damage induced in supercoiled plasmid DNA molecules by low energy (<500 eVu-1) carbon ions has been investigated as a function of ion dose. The production of short linear fragments through multiple double strand breakage is suggested and exponential dose responses for each of the topoisomers are presented.

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U2 - 10.1088/1742-6596/58/1/080

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Conformational changes to plasmid DNA induced by low energy carbon ions

Abstract

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