Comparison of DC Bead-irinotecan and DC Bead-topotecan drug eluting beads for use in locoregional drug delivery to treat pancreatic cancer

Keyphrases

• DC Bead 100%
• Locoregional Drug Delivery 100%
• Drug-eluting Beads 100%
• Irinotecan 100%
• Topotecan 100%
• Pancreatic Cancer 100%
• DEBIRI 80%
• MTS Assay 40%
• Mechanical Properties 20%
• Drug Loading Capacity 20%
• Potential Toxicity 20%
• Drug Delivery 20%
• Hydrogel Matrix 20%
• Embolization 20%
• Doxorubicin 20%
• Drug Loading 20%
• Sustained Drug Release 20%
• Therapeutic Goals 20%
• Tumor Size 20%
• Maximum Load 20%
• Irinotecan Hydrochloride 20%
• Compression Modulus 20%
• Static Loading 20%
• Tolerability 20%
• Polyvinyl Alcohol Hydrogel 20%
• Modified Polyvinyl Alcohol 20%
• Topotecan Hydrochloride 20%
• IC50 20%
• Sulfonate 20%
• Repeated Administration 20%
• Repeated Injection 20%
• Free Drug 20%
• Adenocarcinoma Cells 20%
• Topoisomerase Inhibitors 20%
• Human Pancreatic Adenocarcinoma 20%
• Liver Cancer 20%
• Drug Forms 20%
• Well Tolerated 20%
• Mouse Xenograft Model 20%
• Cytotoxic Efficacy 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Irinotecan 100%
• Pancreas Cancer 100%
• Topotecan 100%
• IC50 16%
• Sustained Release 16%
• Doxorubicin 16%
• DNA Topoisomerase Inhibitor 16%
• Sulfonate 16%
• Tolerability 16%
• Pancreas Adenocarcinoma 16%
• Liver Cancer 16%
• Polyvinyl Alcohol 16%